Hyperemesis gravidarum and long-term health of the offspring

被引：28

作者：

Ayyavoo, Ahila ^{[1
,2
]}

Derraik, Jose G. B. ^{[1
]}

Hofman, Paul L. ^{[1
,2
]}

Cutfield, Wayne S. ^{[1
,2
]}

机构：

[1] Univ Auckland, Liggins Inst, Auckland, New Zealand

[2] Gravida Natl Ctr Growth & Dev, Auckland, New Zealand

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2014年 / 210卷 / 06期

关键词：

childhood; consequences; health; hyperemesis gravidarum; nausea and vomiting of pregnancy; HELICOBACTER-PYLORI INFECTION; HUMAN CHORIONIC-GONADOTROPIN; INSULIN SENSITIVITY; PRENATAL EXPOSURE; WERNICKES ENCEPHALOPATHY; GLUCOSE-TOLERANCE; THYROID-FUNCTION; SKELETAL-MUSCLE; EARLY-PREGNANCY; SEVERE NAUSEA;

D O I：

10.1016/j.ajog.2013.11.035

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Nausea and vomiting of pregnancy is a very common occurrence, but the reported incidence of hyperemesis gravidarum (a more severe form of vomiting in pregnancy) is much lower, estimated to vary from 0.3-3.6%. Studies have shown that nausea and vomiting of pregnancy is associated with improved fetal outcomes, such as lower rates of miscarriage. However, there are limited data on outcomes associated with hyperemesis gravidarum, which have focused on pregnancy and neonatal outcomes. Recently, studies showed adverse health outcomes, such as a reduction in insulin sensitivity in childhood and increased incidence of psychological disorders in adulthood. The effects of hyperemesis gravidarum in the offspring need to be further examined throughout childhood, adolescence, and into adulthood, so that long-term disease risks can be evaluated.

引用

页码：521 / 525

页数：5

共 81 条

[1]

American College of Obstetrics and Gynecology, 2004, Obstet Gynecol, V103, P803

[2] Severe Hyperemesis Gravidarum Is Associated With Reduced Insulin Sensitivity in the Offspring in Childhood [J].