Targeted Metagenomics Offers Insights into Potential Tick-Borne Pathogens

被引:8
作者
Thoendel, Matthew [1 ]
机构
[1] Mayo Clin, Dept Med, Div Infect Dis, Rochester, MN 55905 USA
关键词
DIAGNOSIS;
D O I
10.1128/JCM.01893-20
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Tick-borne disease pathogen identification remains a diagnostic challenge due to the multiple tests necessary for diagnosis. Targeted metagenomic sequencing is an evolving method to detect multiple different pathogens with a single test. In this issue of the Journal of Clinical Microbiology, L. Kingry, S. Sheldon, S. Oatman, B. Pritt, et al. (J Clin Microbiol 58:e00147-20, 2020, https://doi.org/10.1128/JCM.00147-20) explore 16S rRNA gene-targeted metagenomics to identify bacterial pathogens in 881 of more than 13,000 specimens submitted for tick-borne pathogen testing, giving new insights into suspected tick-borne pathogens.
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