Inferior mesenteric vein thrombosis in the setting of testosterone therapy

被引:0
作者
Manongi, Ngoda [1 ]
Byrns, Kory [1 ]
Fulman, Malvina [1 ]
Jaffer, Amir [1 ]
机构
[1] NewYork Presbyterian Queens, Internal Med, Flushing, NY 11355 USA
关键词
Contraindications and precautions; Haematology (drugs and medicines); Medical education; Medical management; VENOUS THROMBOEMBOLISM; THROMBOPHILIA; RISK;
D O I
10.1136/bcr-2022-251886
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Inferior mesenteric vein thrombosis (IMVT) is a rare and potentially lethal complication that can progress to mesenteric ischaemia if left untreated. We report a case of a man in his 70s with a history of polycythaemia vera (PV) with a known negative Janus kinase-2 mutation (JAK2V617) who was started on testosterone therapy 2 months before presenting with left lower quadrant abdominal and flank pain. Evaluation revealed thrombocytosis and IMVT on CT scan. A non-operative approach was deferred for anticoagulation therapy. Within 24 hours, the patient demonstrated significant clinical improvement, and he subsequently made a full recovery. The patient underwent 6 months of anticoagulation therapy with Apixaban. This case documents the first case of IMVT in the setting of PV and testosterone therapy in the literature.
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页数:4
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