Metal-organic framework nanosheets that exhibit pH-controlled drug release

被引：50

作者：

Gao, Xuechuan ^{[1
]}

Cui, Ruixue ^{[1
]}

Zhang, Ming ^{[2
]}

Liu, Zhiliang ^{[1
]}

机构：

[1] Inner Mongolia Univ, Coll Chem & Chem Engn, Hohhot 010021, Peoples R China

[2] Jining Normal Univ, Dept Biol, Ulanchap 012000, Peoples R China

来源：

MATERIALS LETTERS | 2017年 / 197卷

基金：

中国国家自然科学基金;

关键词：

Metal-organic framework; Nanosheets; pH-controlled drug release; Crystal structure; Biomaterials;

D O I：

10.1016/j.matlet.2017.02.082

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Crystalline metal-organic framework (MOF) nanosheets have been fabricated from a new bulk MOF (1) which is assembled by ZnII metal ions as nodes and the drug ibuprofen as ligand. Surfactant-assisted synthetic method was used to control the growth of bulk MOF to obtain MOF nanosheets and the obtained MOF nanosheets exhibit good biodegradability and pH-controlled ibuprofen release. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：217 / 220

页数：4

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