Preparation of dibarbiturates of oxindole by condensation of isatin and barbituric acid derivatives

被引：50

作者：

Jursic, BS ^{[1
]}

Stevens, ED ^{[1
]}

机构：

[1] Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 32期

关键词：

barbituric acid; isatin; oxindole; condensation reactions; isatin-dibarbiturates;

D O I：

10.1016/S0040-4039(02)01107-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A very efficient, simple, and high yield procedure for the isatin condensation with barbituric acid derivatives was described. The condensation reaction is very selective, which is corroborated by following the reaction by NMR, and the structure Of the product was confirmed by X-ray structural analysis. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：5681 / 5683

页数：3

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