Noncovalent interaction-assisted polymeric micelles for controlled drug delivery

被引：161
作者：
Ding, Jianxun [1 ]
Chen, Linghui [2 ]
Xiao, Chunsheng [1 ]
Chen, Li [3 ]
Zhuang, Xiuli [1 ]
Chen, Xuesi [1 ]
机构：
[1] Chinese Acad Sci, Changchun Inst Appl Chem, Key Lab Polymer Ecomat, Changchun 130022, Peoples R China
[2] Jilin Univ, Sch Chem, Changchun 130012, Peoples R China
[3] NE Normal Univ, Dept Chem, Changchun 130024, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 77期
基金：
中国国家自然科学基金;
关键词：
BLOCK-COPOLYMER MICELLES; POLYION COMPLEX MICELLES; OXIDE)-POLY(PROPYLENE OXIDE)-POLY(ETHYLENE OXIDE); POLYLACTIDE/POLY(ETHYLENE GLYCOL) MICELLES; CONJUGATED BETA-CYCLODEXTRIN; HOST-GUEST INTERACTIONS; TRIBLOCK COPOLYMERS; BUILDING-BLOCKS; CO-DELIVERY; VITAMIN-E;
D O I：
10.1039/c4cc03153a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Polymeric micelles are one of the most promising nanovehicles for drug delivery. In addition to amphiphilicity, various individual or synergistic noncovalent interplays including strong hydrophobic, electrostatic, host-guest, hydrogen bonding, stereocomplex and coordination interactions have been recently employed to improve the physical stability of micelles, and even provide them with certain intelligences or bioactivities. Through the ingenious designs and precise preparations, many noncovalent-mediated micelles display great prospects in the realm of controlled drug delivery, and certain species have been promoted to clinical trials. The current review presents the diverse noncovalent interactions that are applied to enhance polymeric micelles as drug nanocarriers, and preliminarily discusses the future directions and perspectives of this field.
引用
收藏
页码：11274 / 11290
页数：17
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  • [151] Synthesis of Paclitaxel-Conjugated β-Cyclodextrin Polyrotaxane and Its Antitumor Activity
    Yu, Shuling
    Zhang, Yajun
    Wang, Xin
    Zhen, Xu
    Zhang, Zhaoheng
    Wu, Wei
    Jiang, Xiqun
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (28) : 7272 - 7277
  • [152] Polylactide-graft-doxorubicin Nanoparticles with Precisely Controlled Drug Loading for pH-Triggered Drug Delivery
    Yu, Yun
    Chen, Chih-Kuang
    Law, Wing-Cheung
    Weinheimer, Emily
    Sengupta, Sanghamitra
    Prasad, Paras N.
    Cheng, Chong
    [J]. BIOMACROMOLECULES, 2014, 15 (02) : 524 - 532
  • [153] Cyclodextrin-assisted assembly of stimuli-responsive polymers in aqueous media
    Yuen, Fanny
    Tam, Kam Chiu
    [J]. SOFT MATTER, 2010, 6 (19) : 4613 - 4630
  • [154] Dynamics of micelles of the triblock copolymers poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) in aqueous solution
    Zana, Raoul
    Marques, Carlos
    Johner, Albert
    [J]. ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2006, 123 (SPEC. ISS.) : 345 - 351
  • [155] Cholic acid-functionalized nanoparticles of star-shaped PLGA-vitamin E TPGS copolymer for docetaxel delivery to cervical cancer
    Zeng, Xiaowei
    Tao, Wei
    Mei, Lin
    Huang, Laigiang
    Tan, Chunyan
    Feng, Si-Shen
    [J]. BIOMATERIALS, 2013, 34 (25) : 6058 - 6067
  • [156] Acid-Activatable Prodrug Nanogels for Efficient Intracellular Doxorubicin Release
    Zhan, Fuxing
    Chen, Wei
    Wang, Zhongjuan
    Lu, Wentao
    Cheng, Ru
    Deng, Chao
    Meng, Fenghua
    Liu, Haiyan
    Zhong, Zhiyuan
    [J]. BIOMACROMOLECULES, 2011, 12 (10) : 3612 - 3620
  • [157] Polyion complex micelles entrapping cationic dendrimer porphyrin: effective photosensitizer for photodynamic therapy of cancer
    Zhang, GD
    Harada, A
    Nishiyama, N
    Jiang, DL
    Koyama, H
    Aida, T
    Kataoka, K
    [J]. JOURNAL OF CONTROLLED RELEASE, 2003, 93 (02) : 141 - 150
  • [158] Folate-conjugated β-cyclodextrin from click chemistry strategy and for tumor-targeted drug delivery
    Zhang, Huaihong
    Cai, Zhaosheng
    Sun, Yu
    Yu, Fei
    Chen, Yaoqiang
    Sun, Baiwang
    [J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2012, 100A (09) : 2441 - 2449
  • [159] Synthesis and Characterization of Tumor-acidity-sensitive Poly (L-lysine) -doxorubicin Conjugates
    Zhang Jian-Cheng
    Ding Jian-Xun
    Xiao Chun-Sheng
    He Chao-Liang
    Zhuang Xiu-Li
    Yang Ya-Nan
    Chen Xue-Si
    [J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2012, 33 (12): : 2809 - 2815
  • [160] Cyclodextrin-based supramolecular systems for drug delivery: Recent progress and future perspective
    Zhang, Jianxiang
    Ma, Peter X.
    [J]. ADVANCED DRUG DELIVERY REVIEWS, 2013, 65 (09) : 1215 - 1233
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