Noncovalent interaction-assisted polymeric micelles for controlled drug delivery

被引:161
|
作者
Ding, Jianxun [1 ]
Chen, Linghui [2 ]
Xiao, Chunsheng [1 ]
Chen, Li [3 ]
Zhuang, Xiuli [1 ]
Chen, Xuesi [1 ]
机构
[1] Chinese Acad Sci, Changchun Inst Appl Chem, Key Lab Polymer Ecomat, Changchun 130022, Peoples R China
[2] Jilin Univ, Sch Chem, Changchun 130012, Peoples R China
[3] NE Normal Univ, Dept Chem, Changchun 130024, Peoples R China
基金
中国国家自然科学基金;
关键词
BLOCK-COPOLYMER MICELLES; POLYION COMPLEX MICELLES; OXIDE)-POLY(PROPYLENE OXIDE)-POLY(ETHYLENE OXIDE); POLYLACTIDE/POLY(ETHYLENE GLYCOL) MICELLES; CONJUGATED BETA-CYCLODEXTRIN; HOST-GUEST INTERACTIONS; TRIBLOCK COPOLYMERS; BUILDING-BLOCKS; CO-DELIVERY; VITAMIN-E;
D O I
10.1039/c4cc03153a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Polymeric micelles are one of the most promising nanovehicles for drug delivery. In addition to amphiphilicity, various individual or synergistic noncovalent interplays including strong hydrophobic, electrostatic, host-guest, hydrogen bonding, stereocomplex and coordination interactions have been recently employed to improve the physical stability of micelles, and even provide them with certain intelligences or bioactivities. Through the ingenious designs and precise preparations, many noncovalent-mediated micelles display great prospects in the realm of controlled drug delivery, and certain species have been promoted to clinical trials. The current review presents the diverse noncovalent interactions that are applied to enhance polymeric micelles as drug nanocarriers, and preliminarily discusses the future directions and perspectives of this field.
引用
收藏
页码:11274 / 11290
页数:17
相关论文
共 50 条
  • [1] Noncovalent interaction-stabilized polymeric micelles for targeted delivery of anticancer drug
    Tan, Jeremy
    Attia, Amalina
    Yang, Chuan
    Gao, Shujun
    Hedrick, James
    Nelson, Alshakim
    Yang, Yi-Yan
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [2] Noncovalent interaction-assisted drug delivery system with highly efficient uptake and release of paclitaxel for anticancer therapy
    Wei, Yuping
    Ma, Liang
    Zhang, Liang
    Xu, Xia
    INTERNATIONAL JOURNAL OF NANOMEDICINE, 2017, 12 : 7039 - 7051
  • [3] Noncovalent interaction-stabilized polymeric micelles for targeted delivery of anticancer drugs
    Tan, Jeremy P. K.
    Attia, Amalina
    Yang, Chuan
    Gao, Shujun
    Hedrick, James L.
    Nelson, Alshakim
    Yang, Yi Yan
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [4] Noncovalent Interaction-Assisted Ferrocenyl Phosphine Ligands in Asymmetric Catalysis
    Zhao, Qingyang
    Chen, Caiyou
    Wen, Jialin
    Dong, Xiu-Qin
    Zhang, Xumu
    ACCOUNTS OF CHEMICAL RESEARCH, 2020, 53 (09) : 1905 - 1921
  • [5] Polymeric micelles for drug delivery
    Croy, S. R.
    Kwon, G. S.
    CURRENT PHARMACEUTICAL DESIGN, 2006, 12 (36) : 4669 - 4684
  • [6] Novel hyperbranched polymeric micelles as controlled drug delivery systems
    Jiang, SA
    Liu, HB
    Guo, J
    Joshi, N
    Uhrich, KE
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1998, 215 : U321 - U321
  • [7] Zwitterionic light-responsive polymeric micelles for controlled drug delivery
    Shen, Hanjian
    Zhou, Min
    Zhang, Qian
    Keller, Andreas
    Shen, Yan
    COLLOID AND POLYMER SCIENCE, 2015, 293 (06) : 1685 - 1694
  • [8] Zwitterionic light-responsive polymeric micelles for controlled drug delivery
    Hanjian Shen
    Min Zhou
    Qian Zhang
    Andreas Keller
    Yan Shen
    Colloid and Polymer Science, 2015, 293 : 1685 - 1694
  • [9] Polymeric micelles for anticancer drug delivery
    Majumder, Nairrita
    Das, Nandita G.
    Das, Sudip K.
    THERAPEUTIC DELIVERY, 2020, 11 (10) : 613 - 635
  • [10] Polymeric micelles for acyclovir drug delivery
    Sawdon, Alicia J.
    Peng, Ching-An
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2014, 122 : 738 - 745