Intermolecular Conjugate Addition of Pyrroloindoline and Furoindoline Radicals to α,β-Unsaturated Enones via Photoredox Catalysis

被引：25

作者：

Zhou, Shupeng ^{[1
]}

Zhang, Deliang ^{[1
]}

Sun, Yu ^{[1
]}

Li, Ruofan ^{[1
]}

Zhang, Wenhao ^{[1
]}

Li, Ang ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2014年 / 356卷 / 13期

基金：

中国国家自然科学基金;

关键词：

alkaloid-terpenoid hybrids; conjugate addition; furoindolines; photoredox catalysis; pyrroloindolines; VISIBLE-LIGHT PHOTOCATALYSIS; C-H BONDS; SYNTHETIC APPLICATIONS; MERGING PHOTOREDOX; CHAIN REACTIONS; CYCLIZATIONS; GENERATION; REACTIVITY; CHEMISTRY; DESIGN;

D O I：

10.1002/adsc.201400702

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

We have developed an intermolecular conjugate addition of 3a-pyrroloindoline/furoindoline radicals to alpha,beta-unsaturated enones, through visible-light photoredox catalysis. Ir(ppy)(2)(dtbbpy) PF6 was found to be an effective promoter to initiate this reaction from readily available 3a-bromopyrroloindolines/furoindolines. This method was exploited to prepare a series of indole terpenoid-like compounds of potential biological interest.

引用

页码：2867 / 2872

页数：6

共 66 条

[41] Dyes as Visible Light Photoredox Organocatalysts [J].