In vitro UV-A protection factor (PF-UVA) of organic and inorganic sunscreens

被引：19

作者：

Couteau, C.

El-Boury, S.

Paparis, E.

Sebille-Rivain, V. ^{[2
]}

Coiffard, L. J. M. ^{[1
]}

机构：

[1] Univ Nantes, Nantes Atlantique Univ, GEP3, Fac Pharm,MMS EA2160, F-44000 Nantes, France

[2] Univ Nantes, Nantes Atlantique Univ, Fac Pharm, Lab Biostat, F-44000 Nantes, France

来源：

PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY | 2009年 / 14卷 / 04期

关键词：

Sunscreens; UVA; effectiveness; photostability; in vitro test; PIGMENT DARKENING PPD; PHOTOSTABILITY; EFFICACY;

D O I：

10.1080/10837450802683966

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The objective of this research was to evaluate the efficacy of various sunscreen agents incorporated into an O/W emulsion. Within the scope of this study only an in vitro method was used. According to selected filter UVA, we can obtain more or less effective creams. With the seven available filters, we can cover a range of values between 2 and 12. In addition to these seven filters absorbing in UVA range, variously coated titanium dioxide and zinc oxide were tested as well. So it appears that the best organic UVA filter is anisotriazine at 10% (PF-UVA = 11.82). Its effectiveness is comparable with that of the titanium dioxide forms used at 25%. Photostability in Suntest (R) showed that the more photostable UVA-filters are the benzophenones.

引用

页码：369 / 372

页数：4

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[3]

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