Enhanced production of astaxanthin by the green microalga Chlorella zofingiensis in mixotrophic culture

被引:151
作者
Ip, PF [1 ]
Wong, KH [1 ]
Chen, F [1 ]
机构
[1] Univ Hong Kong, Dept Bot, Hong Kong, Hong Kong, Peoples R China
关键词
Chlorella zofingiensis; astaxanthin; glucose; nitrate; mixotrophic culture;
D O I
10.1016/j.procbio.2003.08.003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Mixotrophic culture may be used as an efficient means for enhanced production of light-induced pigments in microalgae. The growth and pigments formation of the green microalga Chlorella zofingiensis cultivated at various glucose and nitrate concentrations in mixotrophic culture were investigated. High glucose and low nitrate concentrations favoured the production of astaxanthin in the algal culture. The highest yield of astaxanthin was 12.5 mg l(-1), which was obtained in the medium containing 30 g l(-1) glucose and 0.55 g l(-1) nitrate. The results indicated that supplementation of glucose and nitrate in the culture medium could be effectively manipulated to enhance astaxanthin production by C. zofingiensis in mixotrophic culture. (C) 2003 Elsevier Ltd. All rights reserved.
引用
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页码:1761 / 1766
页数:6
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