A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter

被引：299

作者：

Pereira, LA ^{[1
]}

Bentley, K ^{[1
]}

Peeters, A ^{[1
]}

Churchill, MJ ^{[1
]}

Deacon, NJ ^{[1
]}

机构：

[1] Macfarlane Burnet Ctr Med Res, Natl Ctr HIV Virol Res, AIDS Mol Biol Unit, Fairfield, Vic 3078, Australia

来源：

NUCLEIC ACIDS RESEARCH | 2000年 / 28卷 / 03期

关键词：

D O I：

10.1093/nar/28.3.663

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) represents a model promoter system and the identification and characterisation of cellular proteins that interact with this region has provided a basic understanding about both general eukaryotic and HIV-1 proviral transcriptional regulation. To date a large number of sequence-specific DNA-protein interactions have been described for the HIV-1 LTR. The aim of this report is to provide a comprehensive, updated listing of these HIV-1 LTR interactions, It is intended as a reference point to facilitate on-going studies characterising the identity of cellular proteins interacting with the HIV-1 LTR and the functional role(s) of specific regions of the LTR for HIV-1 replication.

引用

页码：663 / 668

页数：6

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