Tetracyclines: what a rheumatologist needs to know?

被引：3

作者：

Attar, Suzan M. ^{[1
]}

机构：

[1] KAUH, Dept Med, Jeddah, Saudi Arabia

来源：

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES | 2009年 / 12卷 / 02期

关键词：

calcinosis; osteoarthritis; rheumatoid arthritis; sarcoidosis; tetracyclines; DOUBLE-BLIND; SYSTEMIC-SCLEROSIS; ARTHRITIS; DOXYCYCLINE; MINOCYCLINE; PLACEBO; TRIAL;

D O I：

10.1111/j.1756-185X.2009.01389.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Tetracyclines are broad-spectrum antibiotics that act at the ribosomal level. They were first introduced in 1948 and were widely prescribed by dermatologists in the early 1950s for treatment of acne. More recently, biologic actions of tetracyclines affecting inflammation, angiogenesis, and bone metabolism have been researched. The therapeutic effects of tetracycline and its analogues in rheumatic diseases have also been investigated. This article will review the rheumatological use of tetracycline and its analogues.

引用

页码：84 / 89

页数：6

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