Quantitative imaging of pre-mRNA splicing factors in living cells

被引:38
作者
Eils, R
Gerlich, D
Tvaruskó, W
Spector, DL
Misteli, T
机构
[1] Univ Heidelberg, Dept Neurobiol, D-69120 Heidelberg, Germany
[2] Univ Heidelberg, Bioinformat Grp, D-69120 Heidelberg, Germany
[3] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
关键词
D O I
10.1091/mbc.11.2.413
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
[No abstract available]
引用
收藏
页码:413 / 418
页数:6
相关论文
共 14 条
[1]   Three-dimensional reconstruction of painted human interphase chromosomes: Active and inactive X chromosome territories have similar volumes but differ in shape and surface structure [J].
Eils, R ;
Dietzel, S ;
Bertin, E ;
Schrock, E ;
Speicher, MR ;
Ried, T ;
RobertNicoud, M ;
Cremer, C ;
Cremer, T .
JOURNAL OF CELL BIOLOGY, 1996, 135 (06) :1427-1440
[2]   INVIVO EVIDENCE THAT TRANSCRIPTION AND SPLICING ARE COORDINATED BY A RECRUITING MECHANISM [J].
JIMENEZGARCIA, LF ;
SPECTOR, DL .
CELL, 1993, 73 (01) :47-59
[3]   Active and inactive genes localize preferentially in the periphery of chromosome territories [J].
Kurz, A ;
Lampel, S ;
Nickolenko, JE ;
Bradl, J ;
Benner, A ;
Zirbel, RM ;
Cremer, T ;
Lichter, P .
JOURNAL OF CELL BIOLOGY, 1996, 135 (05) :1195-1205
[4]   Structure and function in the nucleus [J].
Lamond, AI ;
Earnshaw, WC .
SCIENCE, 1998, 280 (5363) :547-553
[5]   Interphase chromosomes undergo constrained diffusional motion in living cells [J].
Marshall, WF ;
Straight, A ;
Marko, JF ;
Swedlow, J ;
Dernburg, A ;
Belmont, A ;
Murray, AW ;
Agard, DA ;
Sedat, JW .
CURRENT BIOLOGY, 1997, 7 (12) :930-939
[6]   The cellular organization of gene expression [J].
Misteli, T ;
Spector, DL .
CURRENT OPINION IN CELL BIOLOGY, 1998, 10 (03) :323-331
[7]   Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo [J].
Misteli, T ;
Cáceres, JF ;
Clement, JQ ;
Krainer, AR ;
Wilkinson, MF ;
Spector, DL .
JOURNAL OF CELL BIOLOGY, 1998, 143 (02) :297-307
[8]   Applications of the green fluorescent protein in cell biology and biotechnology [J].
Misteli, T ;
Spector, DL .
NATURE BIOTECHNOLOGY, 1997, 15 (10) :961-964
[9]   The dynamics of a pre-mRNA splicing factor in living cells [J].
Misteli, T ;
Caceres, JF ;
Spector, DL .
NATURE, 1997, 387 (6632) :523-527
[10]   RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo [J].
Misteli, T ;
Spector, DL .
MOLECULAR CELL, 1999, 3 (06) :697-705