Detection of Epstein-Barr virus in leucoreduced blood products

被引:4
作者
Trottier, H. [1 ]
Delage, G. [2 ]
Hu, J. [3 ]
Robitaille, N. [4 ]
Buteau, C. [5 ]
Tucci, M. [6 ]
Lacroix, J. [6 ]
Alfieri, C. [5 ]
机构
[1] Univ Montreal, St Justine Hosp, Dept Social & Prevent Med, Montreal, PQ, Canada
[2] Hema Quebec, Med Affairs, St Laurent, PQ, Canada
[3] St Justine Hosp, Res Ctr, Montreal, PQ, Canada
[4] Univ Montreal, St Justine Hosp, Dept Pediat, Div Hematol Oncol, Montreal, PQ, Canada
[5] Univ Montreal, St Justine Hosp, Dept Pediat, Div Infect Dis, Montreal, PQ, Canada
[6] Univ Montreal, St Justine Hosp, Dept Pediat, Div Pediat Intens Care Med, Montreal, PQ, Canada
关键词
herpesviruses; immunosuppression; leucoreduction; transfusion; transplant; LEUKOREDUCTION; TRANSPLANT; RECIPIENTS; GENOMES; DNA;
D O I
10.1111/vox.12330
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This study examined the prevalence of three human herpesviruses (HHV), namely HHV-4 (Epstein-Barr virus/EBV), HHV-6b and HHV-7 in leucoreduced blood products obtained from the Sainte-Justine Hospital blood bank. A total of 100 specimens, including 34 red blood cell concentrates, 33 platelet bags and 33 plasma units, were collected and screened by a sensitive PCR assay using virus-specific primers. Positive units were then retested by quantitative PCR. Of the 100 specimens, one platelet unit tested positive for EBV.
引用
收藏
页码:199 / 201
页数:3
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