Fatigue in Primary Biliary Cirrhosis

被引：30
|
作者：
Newton, Julia L. [1 ]
机构：
[1] Univ Newcastle, Inst Cellular Med, Sch Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
来源：
CLINICS IN LIVER DISEASE | 2008年 / 12卷 / 02期
关键词：
D O I：
10.1016/j.cld.2008.02.010
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
The autoimmune liver disease, primary biliary cirrhosis (PBC), is associated with debilitating fatigue in a significant proportion of patients. The pathogenesis of fatigue in PBC is unclear, but preliminary studies suggest it has central mechanisms and may have peripheral manifestations, Studies are beginning to elucidate the biological associates of fatigue in PBC, particularly sleep disturbance and autonomic dysfunction. Comprehensive studies, investigating the pathogenesis of fatigue in PBC are urgently needed as are large-scale prospective outcome studies.
引用
收藏
页码：367 / +
页数：18
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