Topical Application of Chinese Herbal Medicine for Atopic Eczema: A Systematic Review with a Meta-Analysis
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作者:
Gu, Sherman
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RMIT Univ, Sch Hlth Sci, Discipline Chinese Med, Melbourne, Vic, AustraliaRMIT Univ, Sch Hlth Sci, Discipline Chinese Med, Melbourne, Vic, Australia
Gu, Sherman
[1
]
Yang, Angela Weihong
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RMIT Univ, Sch Hlth Sci, Discipline Chinese Med, Melbourne, Vic, AustraliaRMIT Univ, Sch Hlth Sci, Discipline Chinese Med, Melbourne, Vic, Australia
Yang, Angela Weihong
[1
]
Li, Chun Guang
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Univ Western Sydney, Ctr Complementary Med Res, Sydney, NSW, AustraliaRMIT Univ, Sch Hlth Sci, Discipline Chinese Med, Melbourne, Vic, Australia
Li, Chun Guang
[2
]
Lu, Chuanjian
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Guangdong Prov Acad Chinese Med Sci, Guangzhou, Guangdong, Peoples R ChinaRMIT Univ, Sch Hlth Sci, Discipline Chinese Med, Melbourne, Vic, Australia
Lu, Chuanjian
[3
]
Xue, Charlie Chang Li
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RMIT Univ, Sch Hlth Sci, Discipline Chinese Med, Melbourne, Vic, Australia
Guangdong Prov Acad Chinese Med Sci, Guangzhou, Guangdong, Peoples R ChinaRMIT Univ, Sch Hlth Sci, Discipline Chinese Med, Melbourne, Vic, Australia
Xue, Charlie Chang Li
[1
,3
]
机构:
[1] RMIT Univ, Sch Hlth Sci, Discipline Chinese Med, Melbourne, Vic, Australia
[2] Univ Western Sydney, Ctr Complementary Med Res, Sydney, NSW, Australia
[3] Guangdong Prov Acad Chinese Med Sci, Guangzhou, Guangdong, Peoples R China
Background: Atopic eczema (AE) affects 10-20% of children in industrialised countries. Objective: This review systematically evaluated the effects and safety of topical use of Chinese herbal medicine (CHM) for AE. Methods: Randomised controlled trials on topical use of CHM were identified through searching electronic databases. Their risk of bias was assessed. Meta-analysis was conducted by employing the RevMan 5.2 software. Results: Ten studies involving 1,058 participants were included. These studies had high risk of bias in randomisation, blinding and outcome data. Meta-analysis showed that topical applications of CHM were superior to conventional medications in total effectiveness rate (risk ratio 1.19; 95% confidence interval 1.04 to 1.36). No significant difference was observed in overall skin lesion score (standardised mean difference -0.05; 95% confidence interval -0.88 to 0.78) compared to corticosteroid creams. Conclusions: There was no conclusive evidence to demonstrate that topical application of CHM for AE was superior to other control interventions due to methodological weaknesses of the included randomised controlled trials. (C) 2014 S. Karger AG, Basel
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页码:294 / 302
页数:9
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[31]
顾恒, 2008, [中华皮肤科杂志, Chinese Journa of Dermatology], V41, P772