Saliva Alternative to Upper Respiratory Swabs for SARS-CoV-2 Diagnosis

被引:40
作者
Byrne, Rachel L. [1 ]
Kay, Grant A. [1 ]
Kontogianni, Konstantina [1 ]
Aljayyoussi, Ghaith [1 ]
Brown, Lottie [1 ]
Collins, Andrea M. [1 ,2 ,3 ]
Cuevas, Luis E. [1 ]
Ferreira, Daniela M. [1 ]
Fletcher, Tom [1 ,3 ]
Fraser, Alice J. [1 ]
Garrod, Gala [1 ]
Hill, Helen [1 ]
Hughes, Grant L. [1 ]
Menzies, Stefanie [1 ]
Mitsi, Elena [1 ]
Owen, Sophie I. [1 ]
Patterson, Edward I. [1 ]
Todd, Stacy [1 ,3 ]
Williams, Christopher T. [1 ]
Hyder-Wright, Angela [1 ,2 ,3 ]
Adams, Emily R. [1 ]
Cubas-Atienzar, Ana I. [1 ]
机构
[1] Univ Liverpool Liverpool Sch Trop Med, Liverpool, Merseyside, England
[2] Natl Inst Hlth Res, Leeds, W Yorkshire, England
[3] Liverpool Univ Hosp Natl Hlth Serv Fdn Trust, Liverpool, Merseyside, England
基金
英国惠康基金;
关键词
D O I
10.3201/eid2611.203283
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
PCR of upper respiratory specimens is the diagnostic standard for severe acute respiratory syndrome coronavirus 2 infection. However, saliva sampling is an easy alternative to nasal and throat swabbing. We found similar viral loads in saliva samples and in nasal and throat swab samples from 110 patients with coronavirus disease.
引用
收藏
页码:2769 / 2770
页数:2
相关论文
共 7 条
[1]  
[Anonymous], 2020, LAB TEST STRAT REC C
[2]   Preparedness and vulnerability of African countries against importations of COVID-19: a modelling study [J].
Gilbert, Marius ;
Pullano, Giulia ;
Pinotti, Francesco ;
Valdano, Eugenio ;
Poletto, Chiara ;
Boelle, Pierre-Yves ;
D'Ortenzio, Eric ;
Yazdanpanah, Yazdan ;
Eholie, Serge Paul ;
Altmann, Mathias ;
Gutierrez, Bernardo ;
Kraemer, Moritz U. G. ;
Colizza, Vittoria .
LANCET, 2020, 395 (10227) :871-877
[3]   The Impact of Repeated Freeze-Thaw Cycles on the Quality of Biomolecules in Four Different Tissues [J].
Ji, Xiaoli ;
Wang, Min ;
Li, Lingling ;
Chen, Fang ;
Zhang, Yanyang ;
Li, Qian ;
Zhou, Junmei .
BIOPRESERVATION AND BIOBANKING, 2017, 15 (05) :475-483
[4]   An overview of technical considerations when using quantitative real-time PCR analysis of gene expression in human exercise research [J].
Kuang, Jujiao ;
Yan, Xu ;
Genders, Amanda J. ;
Granata, Cesare ;
Bishop, David J. .
PLOS ONE, 2018, 13 (05)
[5]  
Nigeria Centre for Disease Control, 2020, National Interim Guidelines for Clinical Management of COVID-19
[6]   Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study [J].
To, Kelvin Kai-Wang ;
Tsang, Owen Tak-Yin ;
Leung, Wai-Shing ;
Tam, Anthony Raymond ;
Wu, Tak-Chiu ;
Lung, David Christopher ;
Yip, Cyril Chik-Yan ;
Cai, Jian-Piao ;
Chan, Jacky Man-Chun ;
Chik, Thomas Shiu-Hong ;
Lau, Daphne Pui-Ling ;
Choi, Chris Yau-Chung ;
Chen, Lin-Lei ;
Chan, Wan-Mui ;
Chan, Kwok-Hung ;
Ip, Jonathan Daniel ;
Ng, Anthony Chin-Ki ;
Poon, Rosana Wing-Shan ;
Luo, Cui-Ting ;
Cheng, Vincent Chi-Chung ;
Chan, Jasper F. W. ;
Hung, Ivan Fan-Ngai ;
Chen, Zhiwei ;
Chen, Honglin ;
Yuen, Kwok-Yung .
LANCET INFECTIOUS DISEASES, 2020, 20 (05) :565-574
[7]   Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes [J].
Zhang, Wei ;
Du, Rong-Hui ;
Li, Bei ;
Zheng, Xiao-Shuang ;
Yang, Xing-Lou ;
Hu, Ben ;
Wang, Yan-Yi ;
Xiao, Geng-Fu ;
Yan, Bing ;
Shi, Zheng-Li ;
Zhou, Peng .
EMERGING MICROBES & INFECTIONS, 2020, 9 (01) :386-389