A highly selective phosphorescent chemodosimeter for cysteine and homocysteine based on platinum(II) complexes

被引：36
作者：
Huang, Kewei
Yang, Hong
Zhou, Zhiguo [1 ]
Chen, Huili
Li, Fuyou
Yi, Tao
Huang, Chunhui
机构：
[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China
来源：
INORGANICA CHIMICA ACTA | 2009年 / 362卷 / 08期
基金：
中国国家自然科学基金;
关键词：
Phosphorescence; Chemodosimeter; Platinum complex; Cysteine; Homocysteine; DIIMINE BIS(ACETYLIDE) COMPLEXES; CROWN-ETHER PENDANT; ACETYLIDE COMPLEXES; ION-BINDING; METAL-IONS; LUMINESCENCE; SENSOR; PHOTOPHYSICS; RECOGNITION; HYDROGEN;
D O I：
10.1016/j.ica.2008.11.026
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A platinum(II) complex Pt(phen)C CC6H4CHO has been demonstrated as a highly selective phosphorescent chemodosimeter for cysteine and homocysteine. Upon addition of homocysteine or cysteine to its acetonitrile-water solution, an evident luminescent color variation from green to orange was observed. This red-shift of phosphorescence emission could be attributed to formation of a thiazinane through a selective reaction of aldehyde group of Pt(phen)C CC6H4CHO with cysteine/homocysteine, which was con. rmed by H-1 NMR investigation and density functional theory (DFT) calculations. The further selectivity investigation indicates that it displays high selectivity for homocysteine and cysteine, and therefore can be utilized as cysteine/homocysteine phosphorescent chemodosimeter. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码：2577 / 2580
页数：4
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