Extended-Spectrum β-Lactamase (ESBL)-Producing Klebsiella pneumoniae in Bulk Tank Milk from Dairy Farms in Indonesia

被引：37
作者：
Sudarwanto, Mirnawati [1 ]
Akineden, OEmer [2 ]
Odenthal, Sabrina [2 ]
Gross, Madeleine [2 ]
Usleber, Ewald [2 ]
机构：
[1] Bogor Agr Univ, Fac Vet Med, Lab Vet Publ Hlth, Bogor, West Java, Indonesia
[2] Univ Giessen, Inst Vet Food Sci, Dairy Sci, D-35390 Giessen, Germany
来源：
FOODBORNE PATHOGENS AND DISEASE | 2015年 / 12卷 / 07期
关键词：
GRAM-NEGATIVE BACTERIA; INTENSIVE-CARE-UNIT; ESCHERICHIA-COLI; ENTEROBACTERIACEAE; MASTITIS; EPIDEMIOLOGY; PREVALENCE; PATHOGENS; HUMANS; GENES;
D O I：
10.1089/fpd.2014.1895
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Bulk tank milk from 80 dairy farms located in the West Java Region of Indonesia was analyzed for the presence of extended-spectrum -lactamase (ESBL)-producing Enterobacteriaceae. Isolates from seven dairy farms were ESBL positive, and all were identified as Klebsiella pneumoniae. The isolates showed ESBL-characteristic antibiotic resistance patterns. Further analysis revealed that all K. pneumoniae isolates harbored the bla(SHV) gene, and two isolates were additionally positive for the bla(TEM-1) and bla(CTX-M-15) genes. Isolates from different farms were clonally diverse according to macrorestriction analysis. The results indicate that the relatively high frequency of ESBL-producing K. pneumoniae in bulk tank milk implies the risk that milk is both a source of local exposure and a vector contributing to the supraregional spread of antibiotic-resistant bacteria by trade.
引用
收藏
页码：585 / 590
页数：6
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