Late-onset Tay-Sachs disease: Adverse effects of medications and implications for treatment

被引：7

作者：

Shapiro, B. E.

Hatters-Friedman, S.

Fernandes-Filho, J. A.

Anthony, K.

Natowicz, M. R.

机构：

[1] Case Western Reserve Univ, Univ Hosp Cleveland, Sch Med, Dept Neurol,Neuromuscular Div, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Univ Hosp Cleveland, Sch Med, Dept Psychiat, Cleveland, OH 44106 USA

[3] Cleveland Clin Fdn, Genomic Med Inst, Cleveland, OH 44195 USA

[4] Cleveland Clin Fdn, Dept Neurol, Cleveland, OH 44195 USA

[5] Cleveland Clin Fdn, Dept Pediat, Cleveland, OH 44195 USA

来源：

NEUROLOGY | 2006年 / 67卷 / 05期

关键词：

D O I：

10.1212/01.wnl.0000233847.72349.b6

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors conducted a retrospective and brief prospective study of adverse effects of approximately 350 medications in 44 adults with late-onset Tay-Sachs disease (LOTS). Some medications were relatively safe, whereas others, particularly haloperidol, risperidone, and chlorpromazine, were associated with neurologic worsening.

引用

页码：875 / 877

页数：3

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