The Practical and Fundamental Limits of Optical Imaging in Mammalian Brains

被引:28
作者
Ji, Na [1 ]
机构
[1] Howard Hughes Med Inst, Ashburn, VA 20148 USA
关键词
MOUSE-BRAIN; MICROSCOPY; RESOLUTION; EXCITATION;
D O I
10.1016/j.neuron.2014.08.009
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Advances in chemistry and physics have profound effects on neuroimaging. Current and future progress in these disciplines will continue to aid in efforts to visualize neural circuitry, particularly in deeper layers of the brain.
引用
收藏
页码:1242 / 1245
页数:4
相关论文
共 19 条
[1]  
Ahrens MB, 2013, NAT METHODS, V10, P413, DOI [10.1038/NMETH.2434, 10.1038/nmeth.2434]
[2]  
[Anonymous], 1995, HIST NEUROSCIENCE
[3]   Structural and molecular interrogation of intact biological systems [J].
Chung, Kwanghun ;
Wallace, Jenelle ;
Kim, Sung-Yon ;
Kalyanasundaram, Sandhiya ;
Andalman, Aaron S. ;
Davidson, Thomas J. ;
Mirzabekov, Julie J. ;
Zalocusky, Kelly A. ;
Mattis, Joanna ;
Denisin, Aleksandra K. ;
Pak, Sally ;
Bernstein, Hannah ;
Ramakrishnan, Charu ;
Grosenick, Logan ;
Gradinaru, Viviana ;
Deisseroth, Karl .
NATURE, 2013, 497 (7449) :332-+
[4]   2-PHOTON LASER SCANNING FLUORESCENCE MICROSCOPY [J].
DENK, W ;
STRICKLER, JH ;
WEBB, WW .
SCIENCE, 1990, 248 (4951) :73-76
[5]   Photon upmanship: Why multiphoton imaging is more than a gimmick [J].
Denk, W ;
Svoboda, K .
NEURON, 1997, 18 (03) :351-357
[6]  
Ghosh KK, 2011, NAT METHODS, V8, P871, DOI [10.1038/NMETH.1694, 10.1038/nmeth.1694]
[7]   Imaging Calcium in Neurons [J].
Grienberger, Christine ;
Konnerth, Arthur .
NEURON, 2012, 73 (05) :862-885
[8]   Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain [J].
Hama, Hiroshi ;
Kurokawa, Hiroshi ;
Kawano, Hiroyuki ;
Ando, Ryoko ;
Shimogori, Tomomi ;
Noda, Hisayori ;
Fukami, Kiyoko ;
Sakaue-Sawano, Asako ;
Miyawaki, Atsushi .
NATURE NEUROSCIENCE, 2011, 14 (11) :1481-U166
[9]  
Helmchen F., 2011, Imaging in Neuroscience and Development, A Laboratory Manual, V1st
[10]  
Horton NG, 2013, NAT PHOTONICS, V7, P205, DOI [10.1038/nphoton.2012.336, 10.1038/NPHOTON.2012.336]