Decreased Viral Load and Symptoms of Polyomavirus-Associated Chronic Interstitial Cystitis after Intravesical Cidofovir Treatment

被引：18

作者：

Eisen, Damon P. ^{[1
]}

Fraser, Ian R. ^{[2
]}

Sung, Linda M. ^{[2
]}

Finlay, Moira

Bowden, Scott ^{[4
]}

O'Connell, Helen ^{[3
]}

机构：

[1] Royal Melbourne Hosp, Victorian Infect Dis Serv, Parkville, Vic 3050, Australia

[2] Royal Melbourne Hosp, Dept Internal Med, Parkville, Vic 3050, Australia

[3] Royal Melbourne Hosp, Dept Urol, Parkville, Vic 3050, Australia

[4] Victorian Infect Dis Reference Lab, Melbourne, Vic, Australia

来源：

CLINICAL INFECTIOUS DISEASES | 2009年 / 48卷 / 09期

关键词：

HEMORRHAGIC CYSTITIS; BK-VIRUS; URINARY-EXCRETION; INSTILLATION; LEFLUNOMIDE; TRANSPLANT; RECIPIENTS;

D O I：

10.1086/597827

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Interstitial cystitis causes disabling bladder pain and is usually diagnosed in the absence of infection. We describe a patient with interstitial cystitis who had high urinary levels of polyomavirus that decreased dramatically after initiation of intravesical cidofovir treatment; the patient also showed substantial improvement in symptoms. Another patient had milder symptoms of cystitis and intermittent polyomavirus shedding. Polyomaviruses, particularly BK virus, may cause some cases of interstitial cystitis.

引用

页码：E86 / E88

页数：3

共 12 条

[11] Leflunomide for polyomavirus type BK nephropathy [J].

Williams, JW ;

Javaid, B ;

Kadambi, PV ;

Gillen, D ;

Harland, R ;

Thistlewaite, JR ;

Garfinkel, M ;

Foster, P ;

Atwood, W ;

Millis, JM ;

Meehan, SM ;

Josephson, MA .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (11) :1157-1158

[12] Age-related urinary excretion of BK polyomavirus by nonimmunocompromised individuals [J].

Zhong, Shan ;

Zheng, Huai-Ying ;

Suzuki, Motofumi ;

Chen, Qin ;

Ikegaya, Hiroshi ;

Aoki, Naoto ;

Usuku, Shuzo ;

Kobayashi, Nobuyoshi ;

Nukuzuma, Souichi ;

Yasuda, Yukiharu ;

Kuniyoshi, Noboru ;

Yogo, Yoshiaki ;

Kitamura, Tadaichi .

JOURNAL OF CLINICAL MICROBIOLOGY, 2007, 45 (01) :193-198

← 1 2 →