PET imaging of the basal ganglia

被引：7
作者：
Laihinen, Arto
Halsband, Ulrike
机构：
[1] Rehamed Neuro GmbH, D-70565 Stuttgart, Germany
[2] Univ Freiburg, Dept Psychol, D-7800 Freiburg, Germany
来源：
JOURNAL OF PHYSIOLOGY-PARIS | 2006年 / 99卷 / 4-6期
关键词：
basal ganglia; neuroimaging; positron emission tomography; neurodegenerative disorders; dopamine; Parkinson's disease;
D O I：
10.1016/j.jphysparis.2006.03.004
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The present chapter reviews PET imaging in basal ganglia disorders; Parkinson's disease is used as a model of these disorders because the neurochemical pathobiology of this disease is well known and great advances in the imaging area have been achieved. Other basal ganglia disorders including Tourette's syndrome, dystonia, Huntington's chorea and Wilson's disease are also dealt with. With PET and SPECT techniques, the whole integrative dopaminergic network of neurons can be studied, which plays an important role in differential diagnostics. Furthermore, pharmacological effects of medication can be visualized and the role of stereotaxic neurosurgery can be evaluated. Finally, functional imaging gives clues about the prognosis and rehabilitation aspects of the basal ganglia disorders. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：406 / 413
页数：8
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