Systemic Adenovirus Infection in Bearded Dragons (Pogona vitticeps): Histological, Ultrastructural and Molecular Findings

被引：25

作者：

Moormann, S. ^{[2
]}

Seehusen, F. ^{[2
]}

Reckling, D. ^{[1
]}

Kilwinski, J. ^{[1
]}

Puff, C. ^{[2
]}

Elhensheri, M. ^{[2
]}

Wohlsein, P. ^{[2
]}

Peters, M. ^{[1
]}

机构：

[1] Staatl Vet Untersuchungsamt Arnsberg, D-59821 Arnsberg, Germany

[2] Univ Vet Med, Dept Pathol, D-30559 Hannover, Germany

来源：

JOURNAL OF COMPARATIVE PATHOLOGY | 2009年 / 141卷 / 01期

关键词：

adenovirus; Bearded Dragon; Pogona vitticeps; BOA CONSTRICTOR; HEPATITIS; DEPENDOVIRUS; VIRUSES; ORIGIN;

D O I：

10.1016/j.jcpa.2009.03.002

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Three Inland Bearded Dragons (Pogona vitticeps) from two breeding groups were humanely destroyed following a period of anorexia. Two of the animals 8-months old and related and one animal was approximately 2-weeks old. Necropsy examination revealed poor bodily condition but no other gross abnormalities. Microscopically there was non-suppurative hepatitis and interstitial nephritis. Multiple large, amphophilic, intranuclear inclusion bodies were present within hepatocytes and epithelial cells of the bile ducts, renal tubules, small and large intestinal mucosa, pancreatic acini and oral mucous membranes. Transmission electron microscopy (TEM) demonstrated that the inclusions comprised viral particles with morphology consistent with an adenovirus. A fragment of the adenoviral polymerase gene was amplified, sequenced and compared with other reptilian adenoviral sequences. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：78 / 83

页数：6

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