Artificial Liver

被引：14

作者：

Sussman, Norman L. ^{[1
]}

Kelly, James H. ^{[2
]}

机构：

[1] Baylor Coll Med, Dept Surg, Houston, TX 77030 USA

[2] Cell Machines Inc, Houston, TX USA

来源：

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY | 2014年 / 12卷 / 09期

关键词：

Artificial Liver; Extracorporeal Liver Assist Device; Bioartificial Liver; Acute Liver Failure; FULMINANT HEPATIC-FAILURE; ASSIST DEVICE; BIOARTIFICIAL LIVER; CONTROLLED-TRIAL; HUMAN FIBROBLASTS; ALBUMIN DIALYSIS; STEM-CELLS; SUPPORT; LINE; HEPATOCYTES;

D O I：

10.1016/j.cgh.2014.06.002

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Artificial liver generally is classified as either inert or cell-based, although only the latter is a true artificial liver. Despite some major achievements and investment, no device is currently available; devices have either not been tested rigorously, or have failed to meet expectations in clinical trials. A successful device will provide the appropriate level of liver function, but it also must be applied in the appropriate clinical setting. An extracorporeal device may be capable of supporting a failing liver, but it will not correct portal hypertension. The future of this field depends on both the technical aspects of the device(s) and their application to the appropriate clinical situation.

引用

页码：1439 / 1442

页数：4

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