Localization of Th-cell subsets in inflammation: differential thresholds for extravasation of Th1 and Th2 cells

被引：75

作者：

D'Ambrosio, D ^{[1
]}

Iellem, A

Colantonio, L

Clissi, B

Pardi, R

Sinigaglia, F

机构：

[1] Roche Milano Ric, Milan, Italy

[2] Hosp San Raffaele, Dibit, Human Immunol Unit, I-20132 Milan, Italy

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 04期

关键词：

D O I：

10.1016/S0167-5699(00)01590-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The recruitment of T helper 1 (Th1) and Th2 cells into peripheral tissues is essential for inflammation and the host response to infections. Here, Daniele D'Ambrosio and colleagues review the traffic signals that enable the distinct positioning of Th1 and Th2 cells and argue that differential thresholds for extravasation constitute a critical aspect of their selective localization to inflamed tissues.

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页码：183 / 186

页数：4

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