Focal Hypoechoic Tumors of Fatty Liver Characterization of Conventional and Contrast-Enhanced Ultrasonography

被引:12
作者
Liu, Li-Ping [2 ]
Dong, Bao-Wei [1 ]
Yu, Xiao-Ling [1 ]
Liang, Ping [1 ]
Zhang, Da-Kun [1 ]
An, Li-Chun [1 ]
机构
[1] Chinese Peoples Liberat Army Gen Hosp, Dept Ultrasound, Beijing 100853, Peoples R China
[2] Shanxi Med Univ, Hosp 1, Dept Ultrasound, Taiyuan, Peoples R China
关键词
contrast agent; fatty liver; hypoechoic liver tumor; ultrasonography; BENIGN HEPATIC-TUMORS; HEPATOCELLULAR-CARCINOMA; NONALCOHOLIC STEATOHEPATITIS; DIAGNOSTIC PERFORMANCE; LESIONS; SONOGRAPHY; AGENT; HEMANGIOMAS; CONFIDENCE; APPEARANCE;
D O I
10.7863/jum.2009.28.9.1133
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Objective. The purpose of this study was to investigate the characteristics of focal hypoechoic tumors of fatty liver using conventional ultrasonography and contrast-enhanced ultrasonography (CEUS). Methods. Sixty-four hypoechoic tumors of fatty liver in 52 patients were examined by both conventional ultrasonography and CEUS. Contrast pulse sequencing and a sulfur hexafluoride contrast agent were used for CEUS. The enhancement patterns were evaluated in real time. Results. Hypoechoic tumors of fatty liver showed posterior echo enhancement, including 71.4% (25 of 35) of hemangiomas, 73.3% (11 of 15) of metastases, and 50.0% (3 of 6) of hepatocellular carcinomas (HCCs) on conventional ultrasonography. During the early arterial phase, 62.5% (5 of 8) of focal nodular hyperplasia lesions showed a central spoked wheel enhancement pattern, whereas the remaining 37.5% (3 of 8) showed eccentric spoked wheel enhancement. During the arterial phase, 97.1% (34 of 35) of hemangiomas showed peripheral enhancement and centripetal fill-in, including ringlike peripheral enhancement (12 of 35), small nodular peripheral enhancement (19 of 35), and massive irregular peripheral enhancement (3 of 35). In total, 76.5% (26 of 34) of hemangiomas were completely filled in. All HCCs showed complete enhancement from 9 to 24 seconds during the arterial phase and began to wash out from 21 to 114 seconds. During the arterial phase, 40.0% (6 of 15) of metastases showed ringlike enhancement; 26.7% (4 of 15) showed slight hyperenhancement; 13.3% (2 of 15) showed hyperenhancement quickly; and the remaining 20.0% (3 of 15) showed heterogeneous hyperenhancement. All metastatic tumors began to wash out from 25 to 40 seconds. In total, 92.2% (59 of 64) of focal hypoechoic tumors of fatty liver were diagnosed as the correct pathologic type with CEUS. Conclusions. With CEUS, characterization of hypoechoic tumors of fatty liver is greatly improved.
引用
收藏
页码:1133 / 1142
页数:10
相关论文
共 25 条
[1]   Characterization of benign hepatic tumors arising in fatty liver with SonoVue and pulse inversion US [J].
Bartolotta, T. V. ;
Midiri, M. ;
Galia, M. ;
Rollandi, G. A. ;
Cademartiri, F. ;
Lagalla, R. ;
Cardinale, A. E. .
ABDOMINAL IMAGING, 2007, 32 (01) :84-91
[2]   Characterization of hypoechoic focal hepatic lesions in patients with fatty liver: diagnostic performance and confidence of contrast-enhanced ultrasound [J].
Bartolotta, Tommaso Vincenzo ;
Taibbi, Adele ;
Galia, Massimo ;
Runza, Giuseppe ;
Matranga, Domenica ;
Midiri, Massimo ;
Lagalla, Roberto .
EUROPEAN RADIOLOGY, 2007, 17 (03) :650-661
[3]   Benign hepatic tumours [J].
Biecker, E ;
Fischer, HP ;
Strunk, H ;
Sauerbruch, T .
ZEITSCHRIFT FUR GASTROENTEROLOGIE, 2003, 41 (02) :191-200
[4]  
CHEN BH, 2007, CHIN J NAT MED, V9, P135
[5]   Nonalcoholic steatohepatitis and hepatocellular carcinoma:: Natural history? [J].
Cotrim, HP ;
Paraná, R ;
Braga, E ;
Lyra, L .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2000, 95 (10) :3018-3019
[6]   Non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma [J].
Cuadrado, A ;
Orive, A ;
García-Suárez, C ;
Domínguez, A ;
Fernández-Escalante, JC ;
Crespo, J ;
Pons-Romero, F .
OBESITY SURGERY, 2005, 15 (03) :442-446
[7]   Evaluation of primary malignancies of the liver using contrast-enhanced sonography: Correlation with pathology [J].
Fan, Zhi-Hui ;
Chen, Min-Hua ;
Dai, Ying ;
Wang, Yan-Bin ;
Yan, Kun ;
Wu, Wei ;
Yang, Wei ;
Yin, Shan-Shan .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2006, 186 (06) :1512-1519
[8]  
Fang Jian Gao, 2005, Zhonghua Gan Zang Bing Za Zhi, V13, P83
[9]  
Guzman G, 2008, ARCH PATHOL LAB MED, V132, P1761, DOI 10.1043/1543-2165-132.11.1761
[10]   Management of hepatic hemangiomas: A 14-year experience [J].
Herman, P ;
Costa, MLV ;
Machado, MAC ;
Pugliese, V ;
D'Albuquerque, LAC ;
Machado, MCC ;
Gama-Rodrigues, JJ ;
Saad, WA .
JOURNAL OF GASTROINTESTINAL SURGERY, 2005, 9 (06) :853-859