Genes and renal disease

被引：23
作者：
Freedman, BI [1 ]
Satko, SG [1 ]
机构：
[1] Wake Forest Univ, Bowman Gray Sch Med, Dept Internal Med, Nephrol Sect, Winston Salem, NC 27157 USA
来源：
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION | 2000年 / 9卷 / 03期
关键词：
D O I：
10.1097/00041552-200005000-00011
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The identification of genetic linkage between polymorphic markers and common kidney diseases, including focal and segmental glomerulosclerosis and diabetic nephropathy, clearly demonstrates that inherited factors contribute to renal failure susceptibility, These breakthroughs reveal the powerful contribution that molecular genetic techniques can make in the search for inherited factors that initiate renal failure and lead to its progression, Additionally, the environmental factors predisposing to nephropathy will be more readily detectable when evaluated in genetically similar populations. This manuscript reviews the developments in genetic epidemiology and molecular genetics of chronic renal failure, Curr Opin Nephrol Hypertens 9:273-277, (C) 2000 Lippincott Williams & Wilkins.
引用
收藏
页码：273 / 277
页数：5
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