Blood Pressure and the Risk of Alzheimer's Disease: Is There a Link?

被引:6
作者
Yuan, Min [1 ]
Chen, Shen-jian [1 ]
Li, Xue-li [1 ]
Xu, Li-jun [1 ]
机构
[1] Nanchang Univ, Affiliated Hosp 2, Dept Neurol, Nanchang 330006, Jiangxi, Peoples R China
来源
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS | 2016年 / 31卷 / 01期
关键词
blood pressure; Alzheimer's disease; neurodegenerative disorder; dementia; ANGIOTENSIN-RECEPTOR BLOCKERS; COGNITIVE FUNCTION; OLD INDIVIDUALS; FOLLOW-UP; HYPERTENSION; DEMENTIA;
D O I
10.1177/1533317515587086
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Alzheimer disease is one of the most common neurodegenerative disorder, and the incidence is increasing. Many epidemiologic studies have considered the association between blood pressure and Alzheimer disease, yet the relationship is still controversial. The objective of this study was to validate whether or not blood pressure is indeed associated with AD. We compared different prospective studies and ultimately found that it is also a controversial issue. Large prospective double-blinded and placebo-controlled studies conducted with the use of standardized outcome measures in different levels are necessary to assess the association of blood pressure and Alzheimer disease.
引用
收藏
页码:97 / 98
页数:2
相关论文
共 17 条
  • [1] IMPACT OF THE TREATMENT OF ISOLATED SYSTOLIC HYPERTENSION ON BEHAVIORAL VARIABLES - RESULTS FROM THE SYSTOLIC HYPERTENSION IN THE ELDERLY PROGRAM
    APPLEGATE, WB
    PRESSEL, S
    WITTES, J
    LUHR, J
    SHEKELLE, RB
    CAMEL, GH
    GREENLICK, MR
    HADLEY, E
    MOYE, L
    PERRY, HM
    SCHRON, E
    WEGENER, V
    [J]. ARCHIVES OF INTERNAL MEDICINE, 1994, 154 (19) : 2154 - 2160
  • [2] Cognitive function and hypertension
    Birns, J.
    Kalra, L.
    [J]. JOURNAL OF HUMAN HYPERTENSION, 2009, 23 (02) : 86 - 96
  • [3] Hypertension Accelerates the Progression of Alzheimer-Like Pathology in a Mouse Model of the Disease
    Cifuentes, Diana
    Poittevin, Marine
    Dere, Ekrem
    Broqueres-You, Dong
    Bonnin, Philippe
    Benessiano, Joelle
    Pocard, Marc
    Mariani, Jean
    Kubis, Nathalie
    Merkulova-Rainon, Tatyana
    Levy, Bernard I.
    [J]. HYPERTENSION, 2015, 65 (01) : 218 - +
  • [4] Blood pressure and dementia in persons 75+years old: 3-year follow-up results from the Kungsholmen Project
    Guo, Zhenchao
    Qiu, Chengxuan
    Viitanen, Matti
    Fastbom, Johan
    Winblad, Bengt
    Fratiglioni, Laura
    [J]. JOURNAL OF ALZHEIMERS DISEASE, 2001, 3 (06) : 585 - 591
  • [5] Angiotensin-Receptor Blockers and Risk of Alzheimer's Disease in Hypertension Population - A Nationwide Cohort Study
    Hsu, Chien-Yi
    Huang, Chin-Chou
    Chan, Wan-Leong
    Huang, Po-Hsun
    Chiang, Chia-Hung
    Chen, Tzeng-Ji
    Chung, Chia-Min
    Lin, Shing-Jong
    Chen, Jaw-Wen
    Leu, Hsin-Bang
    [J]. CIRCULATION JOURNAL, 2013, 77 (02) : 405 - 410
  • [6] Angiotensin-Receptor Blockers, Hypertension and Alzheimer Disease - The Entangled Relationship
    Katayama, Takayuki
    Hasebe, Naoyuki
    [J]. CIRCULATION JOURNAL, 2013, 77 (02) : 315 - 316
  • [7] Kearney PM, 2005, LANCET, V365, P217, DOI 10.1016/S0140-6736(05)70151-3
  • [8] Hypertension is related to cognitive impairment - A 20-year follow-up of 999 men
    Kilander, L
    Nyman, H
    Boberg, M
    Hansson, L
    Lithell, H
    [J]. HYPERTENSION, 1998, 31 (03) : 780 - 786
  • [9] Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial
    Peters, Ruth
    Beckett, Nigel
    Forette, Francoise
    Tuomilehto, Jaakko
    Clarke, Robert
    Ritchie, Craig
    Waldman, Adam
    Walton, Ivan
    Poulter, Ruth
    Ma, Shuping
    Comsa, Marius
    Burch, Lisa
    Fletcher, Astrid
    Bulpitt, Christopher
    [J]. LANCET NEUROLOGY, 2008, 7 (08) : 683 - 689
  • [10] The Association Between Blood Pressure and Incident Alzheimer Disease A Systematic Review and Meta-analysis
    Power, Melinda C.
    Weuve, Jennifer
    Gagne, Joshua J.
    McQueen, Matthew B.
    Viswanathan, Anand
    Blacker, Deborah
    [J]. EPIDEMIOLOGY, 2011, 22 (05) : 646 - 659