A simulated dye method for flow visualization with a computational model for blood flow

被引:40
作者
Kim, T
Cheer, AY
Dwyer, HA
机构
[1] Univ Calif Davis, Dept Math, Davis, CA 95616 USA
[2] Dept Mech Engn, Davis, CA 95616 USA
关键词
computational fluids; unsteady; incompressible; bloodflow; aortic arch; passive scalar; Womersley number;
D O I
10.1016/j.jbiomech.2003.12.028
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A numerical dye method for the visualization of unsteady three-dimensional flow calculations is introduced by coupling the unsteady convection-diffusion equation to the Navier-Stokes equation for mass and momentum. This system of equations is descretized using a finite volume projection-like algorithm with generalized coordinates and overset grids. A powerful pressure prediction method is used to accelerate the convergence of the Pressure Poisson equation. To demonstrate the visualization technique, blood flow through the aortic arch region and the three main arterial branches is computed using various Womersley numbers. In this technique, parcels of fluid are followed in time as a function of the cardiac cycle without having to track individual particles, which in turn aids us to better understand some important aspects of the three-dimensionality of the developing unsteady flow. Using this numerical dye method we analyze the strength of the cross flow during the cardiac cycle, the relationship between the penetration of blood into the aortic branches from its relative position in the ascending aortic region and the effects of the Womersley parameter. This technique can be very useful in the design and development of stents where the topology of the device would require understanding where the blood emanating from the heart ends up at the end of the cardiac cycle. Moreover, this method could be useful in investigating the influence of flow and geometry on the local introduction of medication. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1125 / 1136
页数:12
相关论文
共 22 条
[1]   ARTERIAL WALL SHEAR AND DISTRIBUTION OF EARLY ATHEROMA IN MAN [J].
CARO, CG ;
FITZGERA.JM ;
SCHROTER, RC .
NATURE, 1969, 223 (5211) :1159-+
[2]   SCALAR-VALUED AND PLANAR-VALUED CURVE FITTING USING SPLINES UNDER TENSION [J].
CLINE, AK .
COMMUNICATIONS OF THE ACM, 1974, 17 (04) :218-220
[3]   A SPHERE IN SHEAR-FLOW AT FINITE REYNOLDS-NUMBER - EFFECT OF SHEAR ON PARTICLE LIFT, DRAG, AND HEAT-TRANSFER [J].
DANDY, DS ;
DWYER, HA .
JOURNAL OF FLUID MECHANICS, 1990, 216 :381-410
[4]  
DEBAKEY ME, 1985, ANN SURG, V201, P115
[5]  
DWYER HA, 1998, LECT NOTES PHYS
[6]  
JIN S, 2001, 2001 BIOENG C SNOWB
[7]   PULSATILE FLOW AND ATHEROSCLEROSIS IN THE HUMAN CAROTID BIFURCATION - POSITIVE CORRELATION BETWEEN PLAQUE LOCATION AND LOW AND OSCILLATING SHEAR-STRESS [J].
KU, DN ;
GIDDENS, DP ;
ZARINS, CK ;
GLAGOV, S .
ARTERIOSCLEROSIS, 1985, 5 (03) :293-302
[8]  
Lide D.R., 1997, CRC Handbook of Chemistry and Physics
[9]  
LIU H, 2001, 2001 BIOENG C SNOWB
[10]   Hemodynamic shear stress and its role in atherosclerosis [J].
Malek, AM ;
Alper, SL ;
Izumo, S .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (21) :2035-2042