Er:Yb:NaY2F5O up-converting nanoparticles for sub-tissue fluorescence lifetime thermal sensing

被引:139
作者
Savchuk, Ol. A. [1 ]
Haro-Gonzalez, P. [2 ]
Carvajal, J. J. [1 ]
Jaque, D. [2 ]
Massons, J. [1 ]
Aguilo, M. [1 ]
Diaz, F. [1 ]
机构
[1] Univ Rovira & Virgili, Fis & Cristallog Mat & Nanomat FiCMA FiCNA EMaS, E-43007 Tarragona, Spain
[2] Univ Autonoma Madrid, Fac Ciencias, Dept Fis Mat, Fluorescence Imaging Grp, E-28049 Madrid, Spain
关键词
TEMPERATURE-MEASUREMENTS; THERMOGRAPHIC PHOSPHORS; POLYMERIC THERMOMETER; PHOTOTHERMAL THERAPY; LUMINESCENCE; POLARITY;
D O I
10.1039/c4nr02305f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Non-contact thermometry is essential in biomedical studies requiring thermal sensing and imaging with high thermal and spatial resolutions. In this work, we report the potential use of Er:Yb:NaYF4 and Er:Yb:NaY2F5O up-conversion nanoparticles as thermal sensors by means of lifetime based luminescent thermometry. We demonstrate how Er:Yb:NaY2F5O nanocrystals present a higher thermal sensitivity than the Er:Yb:NaYF4 ones and that their lifetime thermal coefficient is comparable to those corresponding to other nano-sized luminescent systems already used for high resolution lifetime fluorescence thermal sensing. We evaluate the potential use of Er:Yb:NaY2F5O nanoparticles as lifetime based thermal probes by providing the first experimental evidence on sub-tissue lifetime fluorescence thermal sensing by using up-conversion nanoparticles in an ex vivo experiment.
引用
收藏
页码:9727 / 9733
页数:7
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