Er:Yb:NaY2F5O up-converting nanoparticles for sub-tissue fluorescence lifetime thermal sensing

被引：139

作者：

Savchuk, Ol. A. ^{[1
]}

Haro-Gonzalez, P. ^{[2
]}

Carvajal, J. J. ^{[1
]}

Jaque, D. ^{[2
]}

Massons, J. ^{[1
]}

Aguilo, M. ^{[1
]}

Diaz, F. ^{[1
]}

机构：

[1] Univ Rovira & Virgili, Fis & Cristallog Mat & Nanomat FiCMA FiCNA EMaS, E-43007 Tarragona, Spain

[2] Univ Autonoma Madrid, Fac Ciencias, Dept Fis Mat, Fluorescence Imaging Grp, E-28049 Madrid, Spain

来源：

NANOSCALE | 2014年 / 6卷 / 16期

关键词：

TEMPERATURE-MEASUREMENTS; THERMOGRAPHIC PHOSPHORS; POLYMERIC THERMOMETER; PHOTOTHERMAL THERAPY; LUMINESCENCE; POLARITY;

D O I：

10.1039/c4nr02305f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Non-contact thermometry is essential in biomedical studies requiring thermal sensing and imaging with high thermal and spatial resolutions. In this work, we report the potential use of Er:Yb:NaYF4 and Er:Yb:NaY2F5O up-conversion nanoparticles as thermal sensors by means of lifetime based luminescent thermometry. We demonstrate how Er:Yb:NaY2F5O nanocrystals present a higher thermal sensitivity than the Er:Yb:NaYF4 ones and that their lifetime thermal coefficient is comparable to those corresponding to other nano-sized luminescent systems already used for high resolution lifetime fluorescence thermal sensing. We evaluate the potential use of Er:Yb:NaY2F5O nanoparticles as lifetime based thermal probes by providing the first experimental evidence on sub-tissue lifetime fluorescence thermal sensing by using up-conversion nanoparticles in an ex vivo experiment.

引用

页码：9727 / 9733

页数：7

共 54 条

[1] Nanoscale thermometry via the fluorescence of YAG:Ce phosphor particles:: measurements from 7 to 77 °C [J].

Allison, SW ;

Gillies, GT ;

Rondinone, AJ ;

Cates, MR .

NANOTECHNOLOGY, 2003, 14 (08) :859-863

[2] Remote thermometry with thermographic phosphors: Instrumentation and applications [J].

Allison, SW ;

Gillies, GT .

REVIEW OF SCIENTIFIC INSTRUMENTS, 1997, 68 (07) :2615-2650

[3] Fluorescent Thermometers for Dual-Emission-Wavelength Measurements: Molecular Engineering and Application to Thermal Imaging in a Microsystem [J].

Barilero, T. ;

Le Saux, T. ;

Gosse, C. ;

Jullien, L. .

ANALYTICAL CHEMISTRY, 2009, 81 (19) :7988-8000

[4]

Bednarldewicz A., 2010, APPL PHYS B, V103, P847

[5] Quantitative 3D mapping of fluidic temperatures within microchannel networks using fluorescence lifetime imaging [J].

Benninger, RKP ;

Koç, Y ;

Hofmann, O ;

Requejo-Isidro, J ;

Neil, MAA ;

French, PMW ;

deMello, AJ .

ANALYTICAL CHEMISTRY, 2006, 78 (07) :2272-2278

[6] Synthesis of colloidal upconverting NaYF4 nanocrystals doped with Er3+, Yb3+ and Tm3+, Yb3+ via thermal decomposition of lanthanide trifluoroacetate precursors [J].

Boyer, John-Christopher ;

Vetrone, Fiorenzo ;

Cuccia, Louis A. ;

Capobianco, John A. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (23) :7444-7445

[7] LINE-NARROWED FLUORESCENCE-SPECTRA AND SITE-DEPENDENT TRANSITION-PROBABILITIES OF ND3+ IN OXIDE AND FLUORIDE GLASSES [J].

BRECHER, C ;

RISEBERG, LA ;

WEBER, MJ .

PHYSICAL REVIEW B, 1978, 18 (10) :5799-5811

[8] Thermometry at the nanoscale using lanthanide-containing organic-inorganic hybrid materials [J].

Brites, C. D. S. ;

Lima, P. P. ;

Silva, N. J. O. ;

Millan, A. ;

Amaral, V. S. ;

Palacio, F. ;

Carlos, L. D. .

JOURNAL OF LUMINESCENCE, 2013, 133 :230-232

[9] Ratiometric highly sensitive luminescent nanothermometers working in the room temperature range. Applications to heat propagation in nanofluids [J].

Brites, Carlos D. S. ;

Lima, Patricia P. ;

Silva, Nuno J. O. ;

Millan, Angel ;

Amaral, Vitor S. ;

Palacio, Fernando ;

Carlos, Luis D. .

NANOSCALE, 2013, 5 (16) :7572-7580

[10] Thermometry at the nanoscale [J].