Early infection and subsequent insulin dependent diabetes

被引:56
作者
Gibbon, C
Smith, T
Egger, P
Betts, P
Phillips, D
机构
[1] UNIV SOUTHAMPTON,METAB PROGRAMMING GRP,MRC,ENVIRONM EPIDEMIOL UNIT,SOUTHAMPTON,HANTS,ENGLAND
[2] SOUTHAMPTON GEN HOSP,DEPT CHILD HLTH,SOUTHAMPTON,HANTS,ENGLAND
关键词
insulin dependent (type 1) diabetes; infancy; infection; case-control study;
D O I
10.1136/adc.77.5.384
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
In a study of 58 children under the age of 16 with insulin dependent diabetes (IDDM) and 172 matched non-diabetic controls, infection during the first year of life was associated with a reduction in diabetes risk (odds ratio 0.81, 95% confidence interval 0.67 to 0.98, per infective episode). Decreased exposure to common infections during infancy may be linked with subsequent IDDM.
引用
收藏
页码:384 / 385
页数:2
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