Gene screening of Wharton's jelly derived stem cells

被引:13
作者
Alami, S. Mechiche [1 ,2 ]
Velard, F. [1 ,2 ]
Draux, F. [1 ,2 ]
Paredes, F. Siu [1 ,3 ]
Josse, J. [1 ,4 ]
Lemaire, F. [1 ,2 ]
Gangloff, S. C. [1 ,4 ]
Graesslin, O. [5 ]
Laurent-Maquin, D. [1 ,2 ,6 ]
Kerdjoudj, H. [1 ,2 ]
机构
[1] Univ Reims, EA Biomat & Inflammat Site Osseux 4691, SFR Cap Sante, Pole Sante,FED 4231, F-51095 Reims, France
[2] URCA, UFR Odontol, Reims, France
[3] Univ Arequipa, Ctr Biol Mol, Arequipa, Peru
[4] URCA, UFR Pharm, Reims, France
[5] CHU Reims, Dept Gynecol, Reims, France
[6] CHU Reims, Dept Chirurg Dent, Reims, France
关键词
PCR array; human Wharton's jelly stem cells; regenerative medicine; BONE-MARROW; THERAPY;
D O I
10.3233/BME-140974
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Stem cells are the most powerful candidate for the treatment of various diseases. Suitable stem cell source should be harvested with minimal invasive procedure, found in great quantity, and transplanted with no risk of immune response and tumor formation. Fetal derived stem cells have been introduced as an excellent alternative to adult and embryonic stem cells use, but unfortunately, their degree of "stemness" and molecular characterization is still unclear. Several studies have been performed deciphering whether fetal stem cells meet the needs of regenerative medicine. We believe that a transcriptomic screening of Wharton's jelly stem cells will bring insights on cell population features.
引用
收藏
页码:S53 / S61
页数:9
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