Genetic diversity of PRRSV 1 in Central Eastern Europe in 1994-2014: origin and evolution of the virus in the region

被引：54

作者：

Balka, Gyula ^{[1
]}

Podgorska, Katarzyna ^{[2
]}

Brar, Manreetpal Singh ^{[3
]}

Balint, Adam ^{[4
]}

Cadar, Daniel ^{[5
]}

Celer, Vladimir ^{[6
]}

Denes, Lilla ^{[1
]}

Dirbakova, Zuzana ^{[7
]}

Jedryczko, Anna ^{[8
]}

Marton, Lazar ^{[9
]}

Novosel, Dinko ^{[10
]}

Petrovic, Tamas ^{[11
]}

Sirakov, Ivo ^{[12
]}

Szalay, Dora ^{[4
]}

Toplak, Ivan ^{[13
]}

Leung, Frederick Chi-Ching ^{[3
]}

Stadejek, Tomasz ^{[14
]}

机构：

[1] Univ Vet Med, Dept Pathol, Istvan Str 2, H-1076 Budapest, Hungary

[2] Natl Vet Res Inst, Partyzantow 57, PL-24100 Pulawy, Poland

[3] Univ Hong Kong, 5N-12 Kadoorie Biol Sci Bldg, Hong Kong, Hong Kong, Peoples R China

[4] Natl Food Chain Safety Off Vet Diagnost Directora, Tabornok Str 2, H-1149 Budapest, Hungary

[5] Bernhard Nocht Inst Trop Med, WHO Collaborating Ctr Arbovirus & Haemorrhag Feve, Arbovirol, Natl Reference Ctr Trop Infect Dis, Bernhard Nocht Str 74, D-20359 Hamburg, Germany

[6] Univ Vet & Pharmaceut Sci Brno, Inst Infect Dis & Microbiol, Fac Vet Med, Brno 61242, Czech Republic

[7] Vet Inst Zvolen, Drahami 918, Zvolen 96086, Slovakia

[8] Vet Diagnost Lab, PL-11036 Gietrzwald, Poland

[9] Natl Food Chain Safety Off Anim Hlth & Anim Welf, Keleti Karoly Str 24, H-1024 Budapest, Hungary

[10] Univ Zagreb, Fac Agr, Dept Anim Sci, Svetosimunska Cesta 25, Zagreb 10000, Croatia

[11] Sci Vet Inst Novi Sad, Rumenacki Put 20, Novi Sad 21000, Serbia

[12] Med Univ Sofia, Dept Med Microbiol, Fac Med, Zdrave Str 2, Sofia 1431, Bulgaria

[13] Univ Ljubljana, Vet Fac, Natl Vet Inst, Gerbiceva 60, Ljubljana 1000, Slovenia

[14] Warsaw Univ Life Sci SGGW, Dept Pathol & Vet Diagnost, Fac Vet Med, Ul Nowoursynowska 159c, PL-02776 Warsaw, Poland

来源：

SCIENTIFIC REPORTS | 2018年 / 8卷

关键词：

RESPIRATORY SYNDROME VIRUS; IMPACT; DEFINITION; SEQUENCE; STRAINS;

D O I：

10.1038/s41598-018-26036-w

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

More than 20 years after the first outbreaks, the phylogenetic picture of PRRSV is still incomplete and full of gaps, especially in regards of PRRSV 1. Due to the exceptional diversity observed at the eastern borders of Europe and the low number of available sequences from Central Eastern European countries, the authors collected and analyzed both recent as well as already submitted sequences comparing them to a large backbone set of available ORF5 sequences representing the full spectrum of PRRSV 1 Subtype 1 diversity to conduct a systematic phylogenetic analysis and reclassification elucidating the diversity of the virus in these countries. Moreover, further analyses of the EUROSTAT data regarding the live pig movement trends revealed their influence of virus diversity and evolution. The results indicate that besides the effect of local, isolated divergent evolution and the use of modified live vaccines, the most important factor influencing a given country's virus diversity is the transboundary movement of live, infected animals.

引用

页数：12

共 41 条

[11] Holtkamp DJ, 2013, J SWINE HEALTH PROD, V21, P72
[12] Genetic typing of porcine reproductive and respiratory syndrome virus isolates from central European countries
Jackova, A.
Vlasakova, M.
Mandelik, R.
Vilcek, S.
[J]. ACTA VIROLOGICA, 2013, 57 (03) : 363 - 368
[13] Novel structural protein in porcine reproductive and respiratory syndrome virus encoded by an alternative ORF5 present in all arteriviruses
Johnson, Craig R.
Griggs, Theodor F.
Gnanandarajah, Josephine
Murtaugh, Michael P.
[J]. JOURNAL OF GENERAL VIROLOGY, 2011, 92 : 1107 - 1116
[14] Keffaber K., 1989, Am Assoc Swine Prac News, V1, P1
[15] Reorganization and expansion of the nidoviral family Arteriviridae
Kuhn, Jens H.
Lauck, Michael
Bailey, Adam L.
Shchetinin, Alexey M.
Vishnevskaya, Tatyana V.
Bao, Yiming
Ng, Terry Fei Fan
LeBreton, Matthew
Schneider, Bradley S.
Gillis, Amethyst
Tamoufe, Ubald
Diffo, Joseph Le Doux
Takuo, Jean Michel
Kondov, Nikola O.
Coffey, Lark L.
Wolfe, Nathan D.
Delwart, Eric
Clawson, Anna N.
Postnikova, Elena
Bollinger, Laura
Lackemeyer, Matthew G.
Radoshitzky, Sheli R.
Palacios, Gustavo
Wada, Jiro
Shevtsova, Zinaida V.
Jahrling, Peter B.
Lapin, Boris A.
Deriabin, Petr G.
Dunowska, Magdalena
Alkhovsky, Sergey V.
Rogers, Jeffrey
Friedrich, Thomas C.
O'Connor, David H.
Goldberg, Tony L.
[J]. ARCHIVES OF VIROLOGY, 2016, 161 (03) : 755 - 768
[16] Genetic and antigenic characterization of complete genomes of Type 1 Porcine Reproductive and Respiratory Syndrome viruses (PRRSV) isolated in Denmark over a period of 10 years
Kvisgaard, Lise K.
Hjulsager, Charlotte K.
Kristensen, Charlotte S.
Klara, T. Lauritsen
Larsen, Lars E.
[J]. VIRUS RESEARCH, 2013, 178 (02) : 197 - 205
[17] LANYI K, 1993, RUSS E EUR FINANC TR, V29, P68
[18] LINDHAUS W, 1991, PRAKT TIERARZT, V72, P423
[19] Porcine reproductive and respiratory syndrome virus: An update on an emerging and re-emerging viral disease of swine
Lunney, Joan K.
Benfield, David A.
Rowland, Raymond R. R.
[J]. VIRUS RESEARCH, 2010, 154 (1-2) : 1 - 6
[20] Analysis of ORF5 and Full-Length Genome Sequences of Porcine Reproductive and Respiratory Syndrome Virus Isolates of Genotypes 1 and 2 Retrieved Worldwide Provides Evidence that Recombination Is a Common Phenomenon and May Produce Mosaic Isolates
Martin-Valls, G. E.
Kvisgaard, L. K.
Tello, M.
Darwich, L.
Cortey, M.
Burgara-Estrella, A. J.
Hernandez, J.
Larsen, L. E.
Mateu, E.
[J]. JOURNAL OF VIROLOGY, 2014, 88 (06) : 3170 - 3181

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