Construction and Testing of Two Distinct Humanized CD19-Specific Chimeric Antigen Receptors (CARs) for the Treatment of B-Cell Malignancies

被引：0
|
作者：
Gopalakrishnan, Ramakrishnan [1 ]
Matta, Hittu [1 ]
Choi, Sunju [2 ]
Han, Xu [2 ]
Prakash, Rekha [2 ]
Narasappa, Nell [2 ]
Gong, Songjie [2 ]
Chitnis, Saurabh [2 ]
Kahn, Michael [2 ]
Sernas, Jennifer [2 ]
Khan, Prottasha [2 ]
Chaudhary, Preet [2 ]
机构：
[1] Univ So Calif, Ctr Study Blood Dis, Jane Anne Nohl Div Hematol, Los Angeles, CA 90033 USA
[2] Univ So Calif, Los Angeles, CA 90033 USA
来源：
BLOOD | 2016年 / 128卷 / 22期
关键词：
D O I：
10.1182/blood.V128.22.4025.4025
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
4025
引用
收藏
页数：4
相关论文
共 50 条
  • [41] RE: Epigenetic profiling and response to CD19 chimeric antigen receptor T-cell therapy in B-cell malignancies
    Lee, Hwan Young
    Yang, Soo-Bin
    Park, Mi Young
    Baek, Gyung Won
    Kang, Hyoung Jin
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2023, 115 (10): : 1231 - 1233
  • [42] DEVELOPMENT OF CD19-SPECIFIC CENTRAL MEMORY DERIVED T CELL PRODUCTS FOR THE TREATMENT OF CD19+ HEMATOLOGIC MALIGNANCIES
    Wang, X.
    Hamlett, A.
    Bautista, C.
    Wong, C. L. W.
    Chang, W. -C
    Ostberg, J. R.
    Forman, S. J.
    Jensen, M. C.
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2011, 17 (02) : S217 - S217
  • [43] Identification of Predictive Markers of Severe and Prolonged Neutropenia after CD19-Specific CAR T-Cell Treatment in Patients with Relapsed/Refractory B-Cell Malignancies
    Rejeski, Kai
    Berger, Carolina
    Jentzsch, Liv
    Willier, Semjon
    Blumenberg, Viktoria
    Buecklein, Veit
    Faul, Christoph
    Schmidt, Christian
    von Bergwelt, Michael
    Feuchtinger, Tobias
    Bethge, Wolfgang
    Ayuk, Francis A.
    Subklewe, Marion
    BLOOD, 2020, 136
  • [44] Repeat Infusion of CD19-Specific Chimeric Antigen Receptor T-Cell Could Improve the Efficacy with Consistent Safety in Relapsed/Refractory Diffuse Large B-Cell Lymphoma
    Hu, Jianda
    Yang, Ting
    Yang, Xiaozhu
    Xian, Na
    Chen, Yanxin
    Jiang, Peifang
    Huang, Gangxiong
    BLOOD, 2018, 132
  • [45] T Cells Expressing CD19-Specific Chimeric Antigen Receptors Are Inhibited By Indoleamine 2,3-Dioxygenase in Tumors
    Ninomiya, Soranobu
    Huye, Leslie E.
    Savoldo, Barbara
    Dotti, Gianpietro
    Heslop, Helen E.
    Brenner, Malcolm K.
    Rooney, Cliona M.
    Ramos, Carlos A.
    BLOOD, 2014, 124 (21)
  • [46] Bispecific T-cells Expressing Polyclonal Repertoire of Endogenous γδ T-cell Receptors and Introduced CD19-specific Chimeric Antigen Receptor
    Deniger, Drew C.
    Switzer, Kirsten
    Mi, Tiejuan
    Maiti, Sourindra
    Hurton, Lenka
    Singh, Harjeet
    Huls, Helen
    Olivares, Simon
    Lee, Dean A.
    Champlin, Richard E.
    Cooper, Laurence J. N.
    MOLECULAR THERAPY, 2013, 21 (03) : 638 - 647
  • [47] Chimeric Antigen Receptor (CAR) T Cells: Lessons Learned from Targeting of CD19 in B-Cell Malignancies
    Hay, Kevin A.
    Turtle, Cameron J.
    DRUGS, 2017, 77 (03) : 237 - 245
  • [48] Chimeric Antigen Receptor (CAR) T Cells: Lessons Learned from Targeting of CD19 in B-Cell Malignancies
    Kevin A. Hay
    Cameron J. Turtle
    Drugs, 2017, 77 : 237 - 245
  • [49] Neurotoxicity Associated with CD19-specific Chimeric Antigen Receptor T cell Therapy for Adult Acute Lymphoblastic Leukemia (B-ALL)
    Santomasso, Bianca
    Park, Jae Hong
    Riviere, Isabelle
    Mead, Elena
    Li, Daniel
    Senechal, Brigitte
    Purdon, Terrence
    Halton, Elizabeth
    Diamonte, Claudia
    Sadelain, Michel
    Brenjens, Renier
    NEUROLOGY, 2018, 90
  • [50] CD19-specific chimeric antigen receptor-modified (CAR)-T cell therapy for the treatment of chronic lymphocytic leukemia in the ibrutinib era
    Hay, Kevin A.
    Turtle, Cameron J.
    IMMUNOTHERAPY, 2018, 10 (04) : 251 - 254
12345