We present and discuss a variety of mathematical models that have been proposed to capture the dynamic behavior of epidemic processes. We first present traditional group models for which no underlying graph structures are assumed, thus implying that instantaneous mixing between all members of a population occurs. Then we consider models driven by similar principles, but involving non-trivial networks where spreading occurs between connected nodes. We present stability analysis results for selected models from both classes, as well as simple least squares approaches for estimating the spreading parameters of the virus from data for each basic networked model structure. We also provide some simulation models. The paper should serve as a succinct, accessible guide for systems and control research efforts toward understanding and combating COVID-19 and future pandemics.
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Univ Warwick, Coventry CV4 7AL, W Midlands, EnglandUniv Warwick, Coventry CV4 7AL, W Midlands, England
Graham, Matthew
House, Thomas
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Univ Warwick, Coventry CV4 7AL, W Midlands, England
Univ Warwick, Warwick Math Inst, Coventry CV4 7AL, W Midlands, EnglandUniv Warwick, Coventry CV4 7AL, W Midlands, England
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Harbin Inst Technol, Dept Math, Harbin, Heilongjiang, Peoples R China
Addis Ababa Sci & Technol Univ, Addis Ababa, EthiopiaHarbin Inst Technol, Dept Math, Harbin, Heilongjiang, Peoples R China
Tulu, Thomas Wetere
Tian, Boping
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Harbin Inst Technol, Dept Math, Harbin, Heilongjiang, Peoples R ChinaHarbin Inst Technol, Dept Math, Harbin, Heilongjiang, Peoples R China
Tian, Boping
Wu, Zunyou
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Chinese Ctr Dis Control & Prevent, Natl Ctr AIDS STD Control & Prevent, Beijing, Peoples R ChinaHarbin Inst Technol, Dept Math, Harbin, Heilongjiang, Peoples R China