Effect of ALS-associated mutation of ubiquilin 2 on autophagic-lysosome protein degradation

被引:0
|
作者
Idera, Akiko [1 ]
Seki, Takahiro [1 ]
Sato, Masahiro [1 ]
Kurauchi, Yuki [1 ]
Hisatsune, Akinori [2 ,3 ]
Katsuki, Hiroshi [1 ]
机构
[1] Kumamoto Univ, Grad Sch Pharm Sci, Dept Chemicopharmacol Sci, Kumamoto, Japan
[2] Kumamoto Univ, Prior Org Innovat & Excellence, Kumamoto, Japan
[3] Kumamoto Univ, HIGO Program, Program Leading Grad Sch, Kumamoto, Japan
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
2-P-16
引用
收藏
页码:S210 / S210
页数:1
相关论文
共 50 条
  • [1] EXAMINING THE EFFECTS OF MUTATION ON THE AGGREGATION AND DEGRADATION OF AN ALS-ASSOCIATED PROTEIN
    Elder, Mikaela
    Cascarina, Sean
    Brookbank, Lindsey
    Ross, Eric
    PROTEIN SCIENCE, 2019, 28 : 112 - 112
  • [2] ALS-associated FUS mutation reshapes the RNA and protein composition of stress granules
    Mariani, Davide
    Setti, Adriano
    Castagnetti, Francesco
    Vitiello, Erika
    Mecarelli, Lorenzo Stufera
    Di Timoteo, Gaia
    Giuliani, Andrea
    D'Angelo, Angelo
    Santini, Tiziana
    Perego, Eleonora
    Zappone, Sabrina
    Liessi, Nara
    Armirotti, Andrea
    Vicidomini, Giuseppe
    Bozzoni, Irene
    NUCLEIC ACIDS RESEARCH, 2024, 52 (21) : 13269 - 13289
  • [3] A New Mutation in Ubiquilin Gene Family and Its Effect on Protein Degradation
    Yan, Jianhua
    Ajroud, Kaouther
    Fecto, Faisal
    Shi, Yong
    Siddique, Nailah
    Deng, Han-Xiang
    Siddique, Teepu
    NEUROLOGY, 2013, 80
  • [4] Electrochemical Impedance Immunoassay for ALS-Associated Neurofilament Protein: Matrix Effect on the Immunoplatform
    Adil, Omair
    Shamsi, Mohtashim H.
    BIOSENSORS-BASEL, 2023, 13 (02):
  • [5] Prion protein pathology in Ubiquilin 2 models of ALS
    Le, Nhat T.
    Chu, Nam
    Joshi, Gunjan
    Higgins, Nicole R.
    Nebie, Ouada
    Adelakun, Niyi
    Butts, Marie
    Monteiro, Mervyn J.
    NEUROBIOLOGY OF DISEASE, 2024, 201
  • [6] An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity
    Guo, Weirui
    Chen, Yanbo
    Zhou, Xiaohong
    Kar, Amar
    Ray, Payal
    Chen, Xiaoping
    Rao, Elizabeth J.
    Yang, Mengxue
    Ye, Haihong
    Zhu, Li
    Liu, Jianghong
    Xu, Meng
    Yang, Yanlian
    Wang, Chen
    Zhang, David
    Bigio, Eileen H.
    Mesulam, Marsel
    Shen, Yan
    Xu, Qi
    Fushimi, Kazuo
    Wu, Jane Y.
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2011, 18 (07) : 822 - U102
  • [7] An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity
    Weirui Guo
    Yanbo Chen
    Xiaohong Zhou
    Amar Kar
    Payal Ray
    Xiaoping Chen
    Elizabeth J Rao
    Mengxue Yang
    Haihong Ye
    Li Zhu
    Jianghong Liu
    Meng Xu
    Yanlian Yang
    Chen Wang
    David Zhang
    Eileen H Bigio
    Marsel Mesulam
    Yan Shen
    Qi Xu
    Kazuo Fushimi
    Jane Y Wu
    Nature Structural & Molecular Biology, 2011, 18 : 822 - 830
  • [8] Disturbance of proteasomal and autophagic protein degradation pathways by amyotrophic lateral sclerosis-linked mutations in ubiquilin 2
    Osaka, Mayuko
    Ito, Daisuke
    Suzuki, Norihiro
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 472 (02) : 324 - 331
  • [9] A role for the ALS-associated protein FUS/TLS in cellular stress response
    Sama, R. R.
    Bosco, D. A.
    JOURNAL OF NEUROCHEMISTRY, 2013, 125 : 252 - 252
  • [10] A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation
    Fay, James M.
    Zhu, Cheng
    Proctor, Elizabeth A.
    Tao, Yazhong
    Cui, Wenjun
    Ke, Hengming
    Dokholyan, Nikolay V.
    STRUCTURE, 2016, 24 (11) : 1898 - 1906