Histology of Metaplasia and Dysplasia in Barrett's Esophagus

被引：8

作者：

Yerian, Lisa ^{[1
,2
]}

机构：

[1] Cleveland Clin, Lerner Coll Med, Cleveland, OH 44106 USA

[2] Cleveland Clin, Dept Anat Pathol, Cleveland, OH 44195 USA

来源：

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2009年 / 18卷 / 03期

关键词：

Barrett's; Dysplasia; Histology; Metaplasia; Diagnosis; HIGH-GRADE DYSPLASIA; SPECIALIZED INTESTINAL METAPLASIA; GASTROESOPHAGEAL-REFLUX DISEASE; OBSERVER VARIATION; DISTAL ESOPHAGUS; COLUMNAR CELLS; CARDIAC MUCOSA; ADENOCARCINOMA; DIAGNOSIS; JUNCTION;

D O I：

10.1016/j.soc.2009.03.011

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The histologic diagnosis of Barrett's dysplasia requires the identification of intestinal metaplasia, which often presents a challenge due to sampling error, observer variation, and difficulty in histologic interpretation. Particularly problematic is the separation of negative, indefinite, and low-grade dysplasia, the varied histological appearances of high-grade dysplasia, and the diagnosis of suboptimal biopsy material. This article seeks to aid in the histological evaluation of metaplasia and dysplasia, in Barrett's esophagus.

引用

页码：411 / +

页数：13

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