Effects of intradialytic resistance exercise on systemic inflammation in maintenance hemodialysis patients with sarcopenia: a randomized controlled trial

被引：115
作者：
Dong, Zhi-Juan [1 ]
Zhang, Hai-Lin [1 ]
Yin, Li-Xia [2 ]
机构：
[1] First Peoples Hosp Lianyungang, Dept Nursing, 182 Tongguan North Rd, Lianyungang, Jiangsu, Peoples R China
[2] First Peoples Hosp Lianyungang, Dept Hemopurificat Ctr, Lianyungang, Jiangsu, Peoples R China
来源：
INTERNATIONAL UROLOGY AND NEPHROLOGY | 2019年 / 51卷 / 08期
关键词：
Intradialytic resistance exercise; Maintenance hemodialysis; Sarcopenia; Systemic inflammation; SKELETAL-MUSCLE MASS; BODY-COMPOSITION; PROTEIN SUPPLEMENTATION; PHYSICAL-ACTIVITY; MORTALITY; STRENGTH; DIALYSIS; DISEASE; MEN; INTERVENTIONS;
D O I：
10.1007/s11255-019-02200-7
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
PurposeTo investigate the effect of intradialytic resistance exercise on inflammation markers and sarcopenia indices in maintenance hemodialysis (MHD) patients with sarcopenia.MethodsForty-one MHD patients with sarcopenia were divided into an intervention group (group E, n=21) and a control group (group C, n=20). Group C patients only received routine hemodialysis care, whereas group E patients received progressive intradialytic resistance exercise with high or moderate intensity for 12weeks at three times per week (using the weight of the lower limbs and elastic ball movement of the upper limb) on the basis of routine hemodialysis care.ResultsAfter 12weeks, a significant difference in physical activity status (maximum grip strength, daily pace, and physical activity level), Kt/V, and C-reactive protein was found between groups E and C. Inflammatoryfactors (interleukin (IL)-6, IL-10, and tumor necrosis factor(TNF)-alpha) increased or decreased more significantly in group E than in group C.ConclusionsThis study showed that intradialytic resistance exercise can improve physical activity effectively and reduce microinflammatory reactions even if this simple exercise does not affect the muscle mass in MHD patients with sarcopenia.
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收藏
页码：1415 / 1424
页数：10
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