A precisely controlled DNA biped walking device

被引：438
作者：
Sherman, WB [1 ]
Seeman, NC [1 ]
机构：
[1] NYU, Dept Chem, New York, NY 10003 USA
来源：
NANO LETTERS | 2004年 / 4卷 / 07期
关键词：
D O I：
10.1021/nl049527q
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We present an experimental realization of a molecular walking motor built from DNA. The device consists of a biped and a well-defined track where it walks. Input DNA strands act as a convenient interface to allow precise control of the biped walking forward or backward. Psoralen molecules are attached to the ends of the feet in synthesis. When irradiated, the psoralen molecules cross-link strands covalently, allowing unambiguous determination of the state of the walker.
引用
收藏
页码：1203 / 1207
页数：5
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