Influence of morphology on in vitro compatibility of bioactive glasses

被引：30

作者：

Andrade, Angela L.

Valerio, Patricia

Goes, Alfredo M.

Leite, Maria de Fatima

Domingues, Rosana Z.

机构：

[1] Univ Fed Minas Gerais, Dept Chem, BR-31270901 Belo Horizonte, MG, Brazil

[2] Univ Fed Minas Gerais, Dept Physiol & Biophys, BR-31270901 Belo Horizonte, MG, Brazil

[3] Univ Fed Minas Gerais, Dept Biochem & Immunol, BR-31270901 Belo Horizonte, MG, Brazil

来源：

JOURNAL OF NON-CRYSTALLINE SOLIDS | 2006年 / 352卷 / 32-35期

关键词：

biological systems; bioglass; biomaterials; scanning electron microscopy; FTIR measurements; silicates; sol-gel; aerogel and solution chemistry;

D O I：

10.1016/j.jnoncrysol.2006.03.105

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

In vitro bioactivity and biocompatibility of fiber and bulk bioactive glasses were studied. After synthesis with tetraethoxysilane, individual bulk and fiber samples were soaked in a simulated body fluid solution and removed at intervals of 5 and 30 days, respectively. Fourier transform infrared spectroscopic analysis showed hydroxyapatite characteristic P-O vibrational bands for simulated body fluid soaked fibers and bulk samples. Osteoblast viability and alkaline phosphatase production were evaluated by cell incubation in the presence of samples and compared to controls. Fiber glass-incubated osteoblasts showed lower viability but the same alkaline phosphatase production when compared to bulk sample and controls. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：3508 / 3511

页数：4

共 29 条

[1] Si3N4-bioglass composites stimulate the proliferation of MG63 osteoblast-like cells and support the osteogenic differentiation of human bone marrow cells [J].