Y-chromosome STR haplotype diversity in three ethnic populations in Singapore

被引：17

作者：

Yong, R. Y. Y. ^{[1
]}

Lee, L. K. H. ^{[1
]}

Yap, E. P. H. ^{[1
]}

机构：

[1] DSO Natl Labs, Def Med & Environm Res Inst, Singapore 117510, Singapore

来源：

FORENSIC SCIENCE INTERNATIONAL | 2006年 / 159卷 / 2-3期

关键词：

Y-chromosome; short tandem repeats; haplotypes; population data; Asian; allele frequencies; Singapore;

D O I：

10.1016/j.forsciint.2005.05.010

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

In this study, 12 Y-STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS437, DYS438 and DYS439) were genotyped in the three major ethnic populations in Singapore, namely the Chinese, Malay and Indian. Allele frequency distribution, locus diversity, haplotype diversity and discrimination capacity were estimated. Analysis of molecular variance between the three ethnic populations indicated that 87.71% of the haplotypic variation is found within population and 12.29.% is between populations (Fixation Index F-ST = 0.123, p = 0.000). Population pairwise comparisons showed significant Phist values between all population pairs, with the lowest (R-ST = 0.05) for Chinese-Malay and the highest (R-ST = 0.19) for Chinese-Indian. (c) 2005 Elsevier Ireland Ltd. All rights reserved.

引用

页码：244 / 257

页数：14

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