The Prognostic Value of Lymph Node Metastasis with Grade 2 MCTs in Dogs: 55 Cases (2001-2010)

被引:46
作者
Baginski, Heather [1 ]
Davis, Garrett [1 ]
Bastian, Richard P. [2 ]
机构
[1] Red Bank Vet Hosp, Dept Surg, Tinton Falls, NJ 07724 USA
[2] Monmouth Univ, Dept Math, West Long Branch, NJ USA
关键词
MAST-CELL TUMORS; RADIATION-THERAPY; SURGICAL EXCISION; ASSOCIATION; SURVIVAL; EFFICACY; BEHAVIOR;
D O I
10.5326/JAAHA-MS-5997
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
This study evaluates a series of dogs diagnosed with grade 2 cutaneous mast cell tumors (MCTs) with concurrent lymph node (LN) metastasis. All dogs had surgical excision of the primary tumor. The presence of metastasis was confirmed with either histopathology (n = 35) or cytology (n = 20). There was no significant difference in survival times (STs) between dogs with and without LN metastasis. Median survival time (MST) was not reached at 65.9 mo. LN palpation was a poor predictor of metastasis (sensitivity, .71; specificity, .54). Tumor location was the only prognostic factor for survival in this series of dogs. ST was greater for dogs that had removal of their metastatic LN. This study suggests that in dogs with grade 2 MCTs, outcome may not be affected by the presence of LN metastasis; however, removal of the metastatic LN may prolong survival.
引用
收藏
页码:89 / 95
页数:7
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