Callynormine A, a new marine cyclic peptide of a novel class

被引:42
作者
Berer, N
Rudi, A
Goldberg, I
Benayahu, Y
Kashman, Y [1 ]
机构
[1] Tel Aviv Univ, Sch Chem, IL-69978 Ramat Aviv, Israel
[2] Tel Aviv Univ, Dept Zool, IL-69978 Ramat Aviv, Israel
关键词
D O I
10.1021/ol0491787
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel cyclic peptide, callynormine A, was isolated from the Kenyan marine sponge Callyspongia abnormis and its structure elucidated by interpretation of its NMR data and X-ray diffraction analysis. Callynormine A represents a new class of heterodetic cyclic peptides (designated endiamino peptides) possessing an alpha-amido-beta-aminoacrylamide cyclization functionality.
引用
收藏
页码:2543 / 2545
页数:3
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