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Management of postoperative atrial fibrillation after cardiac surgery
被引:17
|作者:
Ha, Andrew C. T.
[1
,2
]
Mazer, Cyril David
[3
,4
]
Verma, Subodh
[4
,5
,6
]
Yanagawa, Bobby
[5
,6
]
Verma, Atul
[2
,4
,7
]
机构:
[1] Univ Hlth Network, Peter Munk Cardiac Ctr, 200 Elizabeth St 3GW-558A, Toronto, ON, Canada
[2] Univ Toronto, Dept Med, Toronto, ON, Canada
[3] Univ Toronto, Dept Anesthesia, Toronto, ON, Canada
[4] St Michaels Hosp, Li Ka Shing Knowledge Inst, 30 Bond St, Toronto, ON M5B 1W8, Canada
[5] Univ Toronto, Dept Surg, Toronto, ON, Canada
[6] St Michaels Hosp, Div Cardiac Surg, 30 Bond St, Toronto, ON M5B 1W8, Canada
[7] Southlake Reg Hlth Ctr, Div Cardiol, Newmarket, Suffolk, England
关键词:
atrial fibrillation;
cardiac surgery;
rate;
rhythm control;
stroke prevention;
POSTPERICARDIOTOMY-SYNDROME;
CARDIOPULMONARY BYPASS;
PERICARDIAL-EFFUSION;
PREVENTION;
ARRHYTHMIAS;
GUIDELINES;
RISK;
METAANALYSIS;
COLCHICINE;
AMIODARONE;
D O I:
10.1097/HCO.0000000000000264
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Purpose of reviewPostoperative atrial fibrillation (POAF) occurs commonly after cardiac surgery and is associated with a number of adverse outcomes. This article will review the available evidence on the prevention and treatment of atrial fibrillation after cardiac surgery. Using this knowledge, we propose a conceptual framework on the management of patients with POAF during various phases after cardiac surgery.Recent findingsPerioperative -blockade is the cornerstone in preventing POAF after cardiac surgery. Results from randomized trials do not support routine use of colchicine or corticosteroids to prevent POAF. There is no study examining the impact of rate versus rhythm control on hard' clinical outcomes such as mortality or stroke in the cardiac surgical population. Furthermore, there is a paucity of research on the optimal timing and choice of oral anticoagulation among POAF cardiac surgical patients who are at risk for stroke.SummaryIn spite of the plethora of therapies available to treat and prevent POAF in the cardiac surgical population, there is little data to address whether they can improve key clinical outcomes such as death or stroke. Guideline recommendations on rate/rhythm control and oral anticoagulation for stroke prevention in the cardiac surgical population are largely extrapolated from studies of nonsurgical atrial fibrillation patients. Further research is needed to address these key atrial fibrillation management issues specific to the cardiac surgical population.
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页码:183 / 190
页数:8
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