Cancer Risk and Surveillance in Primary Sclerosing Cholangitis

被引：42
|
作者：
Folseraas, Trine [1 ,2 ,3 ]
Boberg, Kirsten Muri [1 ,2 ,3 ]
机构：
[1] Oslo Univ Hosp, Rikshosp, Div Canc Med Surg & Transplantat, Dept Transplantat Med,Gastroenterol Sect, N-0424 Oslo, Norway
[2] Oslo Univ Hosp, Rikshosp, Div Canc Med Surg & Transplantat, Norwegian PSC Res Ctr,Dept Transplantat Med, N-0424 Oslo, Norway
[3] Univ Oslo, Rikshosp, Inst Clin Med, N-0027 Oslo, Norway
来源：
CLINICS IN LIVER DISEASE | 2016年 / 20卷 / 01期
关键词：
Primary sclerosing cholangitis; Carcinoma; Dysplasia; Cholangiocarcinoma; Inflammatory bowel disease; Surveillance; Brush cytology; INFLAMMATORY-BOWEL-DISEASE; IN-SITU HYBRIDIZATION; DOSE URSODEOXYCHOLIC ACID; POPULATION-BASED COHORT; ULCERATIVE-COLITIS; LIVER-TRANSPLANTATION; COLORECTAL-CANCER; NATURAL-HISTORY; BRUSH CYTOLOGY; CLINICAL PRESENTATION;
D O I：
10.1016/j.cld.2015.08.014
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Primary sclerosing cholangitis (psq is a chronic, progressive disease characterized by inflammatory and fibrosing strictures of the biliary tree. PSC is associated with a high lifetime risk of hepatobiliary and colorectal cancers. The nature of the carcinogenic process in PSC is not well established. The lack of diagnostic methods for early detection and the limited therapeutic options for cholangiocarcinoma constitute a major challenge in the current handling of PSC patients. The article reviews the risk for cancer development in PSC and discusses surveillance strategies for PSC-associated cancers.
引用
收藏
页码：79 / +
页数：21
相关论文
共 50 条
  • [31] Risk factors for primary sclerosing cholangitis
    Boonstra, Kirsten
    de Vries, Elisabeth M. G.
    van Geloven, Nan
    van Erpecum, Karel J.
    Spanier, Marcel
    Poen, Alexander C.
    van Nieuwkerk, Carin M.
    Witteman, Ben J.
    Tuynman, Hans A.
    Naber, Anton H.
    Kingma, Paul J.
    Beuers, Ulrich
    Ponsioen, Cyriel Y.
    LIVER INTERNATIONAL, 2016, 36 (01) : 84 - 91
  • [32] Primary sclerosing cholangitis
    Joy Worthington
    Roger Chapman
    Orphanet Journal of Rare Diseases, 1
  • [33] Primary sclerosing cholangitis
    Rabiee, Anahita
    Silveira, Marina G.
    TRANSLATIONAL GASTROENTEROLOGY AND HEPATOLOGY, 2021, 6
  • [34] Primary Sclerosing Cholangitis-Associated Cholangiocarcinoma: From Pathogenesis to Diagnostic and Surveillance Strategies
    Catanzaro, Elisa
    Gringeri, Enrico
    Burra, Patrizia
    Gambato, Martina
    CANCERS, 2023, 15 (20)
  • [35] Risk of colorectal cancer in patients with primary sclerosing cholangitis and concomitant inflammatory bowel disease compared with primary sclerosing cholangitis only
    Das, Taranika Sarkar
    Ho, Kimberly
    Udaikumar, Jahnavi
    Chen, Bryan
    Delau, Olivia
    Shaukat, Aasma
    Jacobson, Ira
    Sarwar, Raiya
    HEPATOLOGY RESEARCH, 2024, 54 (09) : 807 - 816
  • [36] Proctocolectomy for colon cancer associated with ulcerative colitis a few months after living donor liver transplantation for primary sclerosing cholangitis: Report of a case
    Fukuhara, Takasuke
    Egashira, Akinori
    Imamura, Masakazu
    Ikegami, Toru
    Oki, Eiji
    Soejima, Yuji
    Sadanaga, Noriaki
    Taketomi, Akinobu
    Yao, Takashi
    Morita, Masaru
    Kakeji, Yoshihiro
    Tsuneyoshi, Masazumi
    Maehara, Yoshihiko
    SURGERY TODAY, 2009, 39 (01) : 59 - 63
  • [37] Risk of colonic neoplasia after liver transplantation for primary sclerosing cholangitis
    Hanouneh, Ibrahim A.
    Macaron, Carole
    Lopez, Rocio
    Zein, Nizar N.
    Lashner, Bret A.
    INFLAMMATORY BOWEL DISEASES, 2012, 18 (02) : 269 - 274
  • [38] Pathogenesis of Primary Sclerosing Cholangitis and Advances in Diagnosis and Management
    Eaton, John E.
    Talwalkar, Jayant A.
    Lazaridis, Konstantinos N.
    Gores, Gregory J.
    Lindor, Keith D.
    GASTROENTEROLOGY, 2013, 145 (03) : 521 - 536
  • [39] Treatment options for primary sclerosing cholangitis
    Sinakos, Emmanouil
    Lindor, Keith
    EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 2010, 4 (04) : 473 - 488
  • [40] Current Therapeutics in Primary Sclerosing Cholangitis
    Tan, Natassia
    Lubel, John
    Kemp, William
    Roberts, Stuart
    Majeed, Ammar
    JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY, 2023, 11 (05) : 1267 - 1281
12345