Single-step recovery of ephedrine hydrochloride from raw materials using expanded bed adsorption

被引:8
作者
Chen, WD [1 ]
Wang, YD [1 ]
Zha, LH [1 ]
Ma, GH [1 ]
Su, ZG [1 ]
机构
[1] Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100080, Peoples R China
基金
中国国家自然科学基金;
关键词
cation resin; chromatography; ephedrine hydrochloride; expanded bed adsorption;
D O I
10.1023/B:BILE.0000036603.35042.70
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Expanded bed adsorption, using a cation resin 001 x 7 Styrene-DVB, was used to recover and purify ephedrine hydrochloride from a powdered herb. The axial liquid-phase dispersion coefficient was about 10(-5) m2 s(-1) and the recovery yield and purification reached 86% and 22, respectively. Compared with using conventional extraction with dimethylbenzene, this method is safer and also more efficient.
引用
收藏
页码:1233 / 1236
页数:4
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