Design and performance analysis of a bio-optical sub-assembly for diffuse optical technologies

被引：1

作者：

Jeong, Je-Myung ^{[1
]}

Park, Kyoungsu ^{[2
]}

Kim, Sehwan ^{[3
]}

机构：

[1] Hanyang Univ, Dept Elect Engn, Seoul 133791, South Korea

[2] Dankook Univ, Dept Med Laser, Cheonan 330714, South Korea

[3] Dankook Univ, Dept Biomed Engn, Coll Med, Cheonan 330714, South Korea

来源：

JOURNAL OF THE KOREAN PHYSICAL SOCIETY | 2014年 / 65卷 / 09期

关键词：

Optical sub-assembly; Laser optical systems; Spectroscopy of tissue diagnostics; BREAST-CANCER; NEOADJUVANT CHEMOTHERAPY; REFLECTANCE SPECTROSCOPY; FREQUENCY-DOMAIN; IN-VIVO; ABSORPTION; TUMORS; WOMEN;

D O I：

10.3938/jkps.65.1379

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

This paper presents a compact, multi-wavelength, and high-frequency-response light source named the bio-optical sub-assembly (BiOSA). The BiOSA is used to measure the absorption and the reduced scattering coefficients from diffuse optics-based biomedical systems. It is equipped with six laser diodes and one optical fiber with a 400-mu m diameter core. Simulations can be used to determine the design parameters and to confirm the feasibility of the BiOSA. The evaluation results indicate that the coupling efficiency of the fabricated BiOSA is 80 85%, and the frequency response is up to 3.38 GHz.

引用

页码：1379 / 1384

页数：6

共 14 条

[1] Improved accuracy in time-resolved diffuse reflectance spectroscopy
Alerstam, Erik
Andersson-Engels, Stefan
Svensson, Tomas
[J]. OPTICS EXPRESS, 2008, 16 (14): : 10440 - 10454
[2] Broadband absorption spectroscopy in turbid media by combined frequency-domain and steady-state methods
Bevilacqua, F
Berger, AJ
Cerussi, AE
Jakubowski, D
Tromberg, BJ
[J]. APPLIED OPTICS, 2000, 39 (34) : 6498 - 6507
[3] Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy
Cerussi, Albert E.
Tanamai, Vaya W.
Hsiang, David
Butler, John
Mehta, Rita S.
Tromberg, Bruce J.
[J]. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 2011, 369 (1955): : 4512 - 4530
[4] Near-infrared absorption and scattering spectra of tissues in vivo
Franceschini, MA
Gratton, E
Hueber, D
Fantini, S
[J]. OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE III, PROCEEDINGS OF, 1999, 3597 : 526 - 531
[5] Design and testing of a miniature broadband frequency domain photon migration instrument
No, Keun-Sik
Kwong, Richard
Chou, Pai H.
Cerussi, Albert
[J]. JOURNAL OF BIOMEDICAL OPTICS, 2008, 13 (05)
[6] Patra T., 2013, INT J INNOV ENG TECH, V2
[7] TIME RESOLVED REFLECTANCE AND TRANSMITTANCE FOR THE NONINVASIVE MEASUREMENT OF TISSUE OPTICAL-PROPERTIES
PATTERSON, MS
CHANCE, B
WILSON, BC
[J]. APPLIED OPTICS, 1989, 28 (12): : 2331 - 2336
[8] Instrumentation and design of a frequency-domain diffuse optical tomography imager for breast cancer detection
Pogue, Brian W.
Testorf, Markus
McBride, Troy
Osterberg, Ulf
Paulsen, Keith
[J]. OPTICS EXPRESS, 1997, 1 (13): : 391 - 403
[9] Design and evaluation of a continuous-wave diffuse optical tomography system
Siegel, AM
Marota, JJA
Boas, DA
[J]. OPTICS EXPRESS, 1999, 4 (08): : 287 - 298
[10] Functional Imaging Using Diffuse Optical Spectroscopy of Neoadjuvant Chemotherapy Response in Women with Locally Advanced Breast Cancer
Soliman, Hany
Gunasekara, Anoma
Rycroft, Mary
Zubovits, Judit
Dent, Rebecca
Spayne, Jacqueline
Yaffe, Martin J.
Czarnota, Gregory J.
[J]. CLINICAL CANCER RESEARCH, 2010, 16 (09) : 2605 - 2614

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