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Current surgical standards of care in Wilms tumor
被引:51
|作者:
Kieran, Kathleen
[1
]
Ehrlich, Peter F.
[2
]
机构:
[1] Seattle Childrens Hosp, Div Urol, Seattle, WA 98109 USA
[2] Univ Michigan Hlth Syst, Ann Arbor, MI USA
关键词:
Wilms tumor;
Surgery;
Pediatric;
NEPHRON-SPARING SURGERY;
CONGESTIVE-HEART-FAILURE;
RENAL-FUNCTION OUTCOMES;
LAPAROSCOPIC NEPHRECTOMY;
RADICAL NEPHRECTOMY;
INITIAL TREATMENT;
ACTINOMYCIN-D;
CHILDREN;
EXPERIENCE;
EXTENSION;
D O I:
10.1016/j.urolonc.2015.05.029
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Background: Wilms tumor (WT) is the second most common abdominal tumor in children. Methods: This chapter discusses surgical considerations for the management of unilateral and bilateral WT. Results: Currently, survival exceeds 90%, owing to multicenter studies under the auspices of the Children's Oncology Group and Societe Internationale d'Oncologie Pediatrique. Surgical excision remains the mainstay of oncologic control and is also crucial for proper staging of disease in order to direct adjuvant therapy and limit treatment-related morbidity. Conclusions: Careful attention must be paid to proper disease staging, upfront and adjuvant therapy, and surgical technique in order to optimize oncologic outcomes while minimizing short- and long-term morbidity. (C) 2016 Elsevier Inc. All rights reserved.
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页码:13 / 23
页数:11
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